Jungwoo 50% Glucose Injection

Key information summary

Efficacy & effects

This medication is used to replenish the body's energy in cases of hyperkalemia, circulatory collapse, and hypoglycemia. It also aids in providing necessary fluids and energy during the treatment of heart disease and is used in cases of poisoning due to drugs or toxins. The primary purpose is to stabilize the patient's condition by maintaining electrolyte balance and supplying energy. Therefore, it is effectively utilized in the treatment of hyperkalemia, heart disease, and poisoning.

Dosage

Administer 20-500 mL via intravenous injection. The rate of intravenous infusion should be no more than 0.5 g/kg per hour as glucose. Use an appropriate amount for the dissolution and dilution of the injection. Adjust according to age and symptoms.

Precautions

When using this drug in ampoule form, care must be taken to cut it cautiously as glass fragments may get mixed in, especially when used for children or the elderly. The glucose contained in this drug can increase the consumption of thiamine (vitamin B₁) during intravenous injection, potentially leading to fatal deficiency, so caution is required. This drug should not be administered to patients with storage dehydration, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucose intolerance, anuria, or hepatic coma. Additionally, it should not be used in patients with spinal hemorrhage or intracranial hemorrhage, and caution should be exercised in severely dehydrated patients as it may worsen hyperosmolar conditions. Administration should be careful in patients with tendencies for potassium, phosphate, or magnesium deficiency, as well as in those with hyponatremia, diabetes insipidus, renal failure, heart failure, severe malnutrition, thiamine deficiency, sepsis, severe trauma, shock states, chronic uremia, and diabetes. Rapid administration of this drug in large amounts can cause electrolyte loss, and exceeding the recommended dose may result in elevated bilirubin and lactate levels, so caution is necessary. Adverse reactions may occur, including hypokalemia, hyperosmolar coma, acidosis, dehydration, hyperosmolarity, polyuria, fluid overload, congestion, pulmonary edema, phlebitis, thrombosis, and injection site pain. Prolonged administration may affect insulin production, so insulin may need to be administered if necessary, and blood glucose and electrolyte levels should be monitored regularly while considering fluid balance. During pregnancy, there may be risks to the fetus, so it should only be used when the therapeutic benefits outweigh the risks. During delivery, issues such as hyperglycemia and hypoglycemia may occur for both the mother and newborn, so careful judgment is required. Children and newborns have immature fluid and electrolyte regulation abilities, so blood glucose and electrolyte levels should be closely monitored, particularly as there may be an increased risk of intracranial hemorrhage in premature or low birth weight infants. Elderly patients have decreased bodily functions, so extra caution is needed during administration. In cases of overdose, hyperglycemia and diabetes may occur, necessitating insulin treatment. Subcutaneous injections may induce circulatory failure due to electrolyte movement in the plasma and are associated with significant local irritation, so they should be avoided; any remaining medication should be discarded after opening and used immediately. Due to the risk of infection during injection, hygiene should be maintained, and the solution should be warmed to body temperature during cold periods. Abrupt discontinuation after the administration of concentrated solutions may induce hypoglycemia, so it should be adjusted gradually, and the potential for interactions and adverse reactions should be thoroughly considered when administered with other medications. To prevent air embolism, avoid injecting air into the container and refrain from continuous connection administration.

Side effects

Hypokalemia, acidosis, dehydration, hyperosmolarity, polyuria, fluid or solute overload, electrolyte imbalance, congestion, pulmonary edema, hyperglycemia, renal loss, fever, phlebitis, thrombosis, blood leakage, injection site pain, uremia

Alternatives / Same-ingredient medications

• Jungwoo 5% Glucose Injection

  Same ingredient
• Jungwoo 20% Glucose Injection

  Same ingredient
• Daehan Glucose Injection (10%)

  Same ingredient
• Daehan Glucose Injection (20%)

  Same ingredient

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