Daehan Glucose Injection (20%)

Key information summary

Efficacy & effects

This medication is used to regulate potassium levels in the blood in cases of electrolyte disorders such as hyperkalemia and circulatory collapse, and to provide energy in case of hypoglycemia. It is also used to improve the patient's condition through hydration and energy supply related to heart symptoms. Additionally, it is utilized for therapeutic purposes in situations of poisoning by drugs or toxins. Thus, it is used to assist in the stable restoration and treatment of physiological functions in various conditions.

Dosage

Administer 20–500 mL intravenously. The infusion rate for intravenous injection should not exceed 0.5g/kg per hour for glucose. Use an appropriate amount for the dissolution and dilution of the injection. Adjust according to age and symptoms.

Precautions

Care should be taken when breaking the ampoule because glass fragments may mix with the solution, especially when administering to children or the elderly. Patients receiving this medication via intravenous injection containing glucose should be monitored for the risk of vitamin B1 deficiency. This medication should not be used in patients with certain conditions such as hypervolemia, dehydration, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucose intolerance, anuria, or hepatic coma. The high-concentration form of this medication is not administered to patients with spinal hemorrhages or intracranial hemorrhages, and high-concentration glucose solutions should be avoided in cases of severe dehydration. Care should be taken when administering to patients with deficiencies of potassium, phosphate, magnesium, or those with hyponatremia, diabetes insipidus, renal failure, heart failure, thiamine deficiency, sepsis, or severe illnesses. Rapid, excessive administration of this medication can lead to electrolyte imbalances or fluid overload, necessitating careful regulation of the administration speed and amount. Overdose may cause increased levels of bilirubin and lactic acid in the blood, and side effects such as hypokalemia, hyperosmolar coma, acidosis, dehydration, and hyperosmolarity may occur. Intravenous administration may cause fluid imbalance, congestion, pulmonary edema, and pain, inflammation, or thrombosis at the injection site, so caution is advised. Long-term use may affect insulin secretion, thus insulin treatment may be necessary. In situations requiring blood glucose control, frequent monitoring of blood glucose and electrolyte levels is advised, and attention should be paid to fluid balance. During pregnancy, the effects on the fetus are not clearly defined, so it should only be administered when absolutely necessary, and maternal and neonatal blood glucose levels should be closely monitored during labor. In children or neonates, fluid and electrolyte regulation abilities may be impaired, so careful monitoring of blood glucose and electrolyte levels is essential, especially in low-birth-weight infants, where the administration rate should be adjusted. Elderly patients may have reduced physical function; therefore, this medication should be used cautiously. In cases of overdose, hyperglycemia and symptoms of diabetes may appear, requiring insulin administration to control. Subcutaneous injections can cause local irritation and circulatory failure, so it is recommended to avoid them, and opened medication should be used immediately, discarding any leftovers. Caution should be taken regarding the risk of infection during injection, and it is advisable to warm the medication to body temperature before administration. When used in conjunction with other medications, potential chemical interactions and adverse reactions should be thoroughly considered and carefully monitored.

Side effects

Hypokalemia, acidosis, dehydration, hyperosmolarity, polyuria with glucose detection, thrombosis, blood leakage, injection site pain, uremia, fever, phlebitis, fluid-electrolyte imbalance, congestion, pulmonary edema, hyperglycemia, renal loss, serum electrolyte imbalance, hypoglycemia, hyperglycemia, local irritation, thrombophlebitis, agglutination reactions, potential adverse reactions upon concurrent administration with blood, risk of air embolism

Alternatives / Same-ingredient medications

• Jungwoo 5% Glucose Injection

  Same ingredient
• Jungwoo 20% Glucose Injection

  Same ingredient
• Jungwoo 50% Glucose Injection

  Same ingredient
• Daehan Glucose Injection (10%)

  Same ingredient

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