Jungwoo 20% Glucose Injection

Key information summary

Efficacy & effects

First, rapid energy supply is needed in cases of hyperkalemia, circulatory collapse, and hypoglycemia. Second, for patients with heart disease, it is crucial to provide hydration and energy alongside therapies G, I, and K. Finally, in cases of drug or poison overdose, appropriate treatments and necessary supplies should be provided. This medication is effectively used in these various situations and helps improve the patient's condition.

Dosage

Administer 20-500mL via intravenous injection. The rate of intravenous infusion should be less than 0.5g/kg/hour as glucose. Use an appropriate amount for dilution of the injectable. Adjust dosage according to age and symptoms.

Precautions

Caution should be taken when opening the container, especially when administering to children or the elderly, as glass fragments may be present in the ampoule injectable. Patients receiving intravenous administration of this medication containing glucose should be cautious as vitamin B1 may be rapidly depleted, leading to severe deficiency symptoms. This medication should not be used in patients with specific conditions such as dehydration, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucose intolerance, anuria, hepatic coma, and other relevant diseases. It should not be administered in high-concentration form to patients with spinal hemorrhage or intracranial hemorrhage, and caution is necessary in severely dehydrated patients as it may worsen hyperosmolar status. For patients with tendencies towards potassium, phosphate, and magnesium deficiencies, or those with hyponatremia, diabetes insipidus, renal failure, heart failure, and severe patients, this medication should be used cautiously, and particular attention is needed for patients receiving specific steroids or diabetic patients. Rapid or large administrations may lead to electrolyte imbalances, fluid overload, pulmonary edema, etc., so the rate of administration and dosage should be adjusted. Additionally, excessive administration of this medication may increase bilirubin and lactate levels, and adverse reactions such as hypokalemia, hyperosmolar coma, acidosis, and polyuria may occur. Long-term administration may affect insulin secretion, so insulin should be given if necessary, and blood glucose and electrolyte levels should be regularly monitored. The safety of this medication during pregnancy has not been sufficiently confirmed, and it should be used cautiously considering potential risks to the fetus, particularly during labor when monitoring the blood glucose levels of both the mother and newborn is crucial. When administering to pediatric patients or newborns, fluid and electrolyte regulation capabilities may be immature, so blood glucose and electrolyte levels should be closely monitored, especially as low birth weight infants have an increased risk of intracranial hemorrhage. Elderly patients should be treated with extra caution due to diminished body function. In cases of overdose, hyperglycemia or diabetes symptoms may appear, so insulin therapy should be implemented as necessary. Subcutaneous administration is not recommended due to the risk of circulatory failure from electrolyte movement in plasma and significant local irritation. After opening, it should be used immediately, and any remaining medication should be discarded, as there is a risk of infection, particularly during infusion. It is advisable to warm this medication to body temperature before use, and caution should be exercised during administration of high-concentration fluids to avoid the risk of thrombophlebitis. Abrupt discontinuation of administration may trigger hypoglycemia, so it should be tapered gradually; also, care should be taken when administering simultaneously with blood products due to potential agglutination reactions. When mixing with other medications, it’s essential to fully understand potential chemical and physical interactions and to monitor closely, using the mixture immediately after preparation to minimize risks. This medication must be stored in a sealed container to prevent air or moisture ingress, thus preserving its efficacy and preventing degradation.

Side effects

Hypokalemia, hyperosmolar coma, acidosis, dehydration, hyperosmolarity, polyuria, fluid or solute overload, fluid-electrolyte imbalance, congestion, pulmonary edema, hyperglycemia, renal loss, fever, phlebitis, thrombosis, extravasation, injection site pain, uremia

Alternatives / Same-ingredient medications

• Jungwoo 5% Glucose Injection

  Same ingredient
• Jungwoo 50% Glucose Injection

  Same ingredient
• Daehan Glucose Injection (10%)

  Same ingredient
• Daehan Glucose Injection (20%)

  Same ingredient

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