Amorex Tablet 375 mg

Adult dose

Adults and children over 12 years of age or those weighing 40 kg and above: Amoxicillin/Clavulanate Potassium 250 mg/125 mg once every 8 hours by mouth, three times a day. In cases of severe and respiratory infections, it can be increased to 500 mg/125 mg once. In cases of renal impairment, dose adjustments should be made based on creatinine clearance. - For creatinine clearance levels of 30 mL/min or higher: continue the usual dosage.

Child dose

The same dosage as adults and children over 12 years of age or those weighing 40 kg and above, adjusted similarly in cases of renal impairment.

This drug should not be administered to patients with a history of hypersensitivity to penicillins or cephalosporins as it is a beta-lactam antibiotic. Caution is required for patients with viral infections such as infectious mononucleosis and lymphocytic leukemia, as the risk of rash may increase. Patients with a history of liver dysfunction or jaundice due to this drug or penicillin should avoid use due to the risk of recurrence. Patients with impaired liver function or severe renal impairment may have increased drug levels, so dosing intervals should be adjusted or careful monitoring should be performed. Patients with allergies or gastrointestinal symptoms such as vomiting and diarrhea should also exercise caution when taking this drug. This drug may cause gastrointestinal adverse reactions such as diarrhea, abdominal pain, and vomiting, and in severe cases may lead to pseudomembranous colitis, so it is important to stop taking it immediately in case symptoms occur. Rarely, liver function abnormalities may appear, and regular liver function tests should be conducted for the elderly or during prolonged usage. Skin rashes, itching, and severe skin reactions such as Stevens-Johnson syndrome may occur, so immediate medical attention is required if symptoms develop. Blood-related adverse reactions such as transient leukopenia or anemia have been reported, so monitoring is necessary if abnormal symptoms occur. Rarely, neurological symptoms such as headache, dizziness, and seizures may occur, so immediate reporting is necessary if neurological symptoms arise. Patients with renal function issues may suffer kidney damage and require regular check-ups, with discontinuation of use if symptoms appear. This drug may affect the balance of intestinal bacteria, leading to candida infections or stomatitis, and treatment is necessary if such symptoms arise. There is a risk of bleeding due to vitamin K deficiency, so elderly patients or those at risk of vitamin deficiency should be cautious. This drug may interact with other medications, especially anticoagulants, probenecid, and allopurinol, so consultation with a specialist is necessary when used in combination. Use should be avoided during the first three months of pregnancy, and women who are pregnant or breastfeeding should carefully weigh the risks and benefits of using this drug. It is not recommended for children under 12 years of age or weighing less than 40 kg. Due to decreased physical function, elderly patients may experience adverse reactions more easily, so dosage and administration intervals should be adjusted and closely monitored. Some clinical test results, such as urine glucose tests, may be distorted while taking this medication, so it is important to inform the physician during examinations. In case of overdose, gastrointestinal symptoms, renal impairment, and allergic reactions may occur, and immediate discontinuation and appropriate treatment are necessary. This medication should be stored in a dry place below 25 degrees, and to prevent the occurrence of resistant bacteria during prolonged use, it is advisable to use it for the shortest duration necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanying cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination problems.

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This drug is stored in a tightly sealed container to prevent moisture, and it is advisable to maintain a cool temperature between 1 to 25 degrees during storage. This preserves the drug's efficacy and prevents deterioration.

Appearance

It is a white or almost white, oval-shaped film-coated tablet.

Package unit

80 tablets/box [(8 tablets/PTP×10)], 100 tablets/box [(10 tablets/PTP×10)]