Medication info

Nequpam Injection Solution (Nepafenac)

Prescription medicationIntravenous injection
Ingredient · strength
Nefopam Hydrochloride›10mg / 1mL
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
A transparent glass ampoule containing a colorless, transparent, odorless liquid.
Packaging
2mL × 10 ampoules, 4mL × 10 ampoules, 10mL × 10 ampoules
Approval status
Active

MFDS item code 201400981 · Notified 2014.03.03

Summary

Main use
Relief of acute pain (postoperative pain)
Who receives it
Adults
Adult administration
Inject 20 mg of nefopam hydrochloride intramuscularly or intravenously per dose. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer the intravenous injection slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. If administered after being added to an infusion solution such as an electrolyte or glucose solution, administer 30mg over 4 hours or 40mg over 6-8 hours, in proportion to the administration time. It is recommended to avoid mixing this medicine with other medicines for injection. The dose may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of acute pain (postoperative pain)

  • Acute pain
  • postoperative pain
View approved original text

This medication is used for symptomatic treatment of acute pain. It is particularly effective in relieving pain that occurs after surgery. Patients can take it with peace of mind as it helps manage postoperative pain. It quickly reduces pain and aids rapid return to daily activities. This medication focuses on pain relief and supports the patient's recovery. Therefore, it is safely used for the relief of acute pain.

How it is given

Adult administration

Inject 20 mg of nefopam hydrochloride intramuscularly or intravenously per dose. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer the intravenous injection slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. If administered after being added to an infusion solution such as an electrolyte or glucose solution, administer 30mg over 4 hours or 40mg over 6-8 hours, in proportion to the administration time. It is recommended to avoid mixing this medicine with other medicines for injection. The dose may be adjusted as appropriate according to age and symptoms.

Precautions

Since this medication is in injection form, the glass ampoule should be carefully cut. If glass fragments mix with the medication, side effects may occur. This medication should not be used in certain patients. For example, it should not be administered to patients with epilepsy or myocardial infarction, those taking certain antidepressants known as MAO inhibitors, individuals allergic to this medication or its ingredients, children under 15 years of age, patients with a history of seizures, those with urinary retention due to urethral or prostate issues, and glaucoma patients with increased eye pressure. Elderly individuals, pregnant or breastfeeding women, and patients taking anticholinergic medications should be especially cautious when using this medication. Side effects may include loss of appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, increased heart rate, dry mouth, urinary retention, injection site pain, headaches, blurred vision, fatigue, nervousness, sleep disturbances, insomnia, agitation, hallucinations, drug dependence, seizures, and allergic reactions. The occurrence of these side effects may vary with the dosage and usually disappears with repeated use. When using this medication for inflammation or pain treatment, the underlying cause must be addressed first, and it should be administered appropriately based on the severity of acute symptoms. Long-term use should be avoided. This medication should be used in conjunction with other antibiotics or antifungals when treating infectious inflammation, and caution is necessary as the diagnosis of an infection may be delayed. In elderly patients, it should be used at the minimal effective dose and carefully monitored, as patients with compromised liver or kidney function may be affected in terms of drug metabolism and excretion. This medication may cause drowsiness or decreased alertness. Therefore, it is advisable not to use it when driving vehicles or operating hazardous machinery. Consult a doctor when using this medication in conjunction with other analgesics or specific medications, as side effects may increase. Pregnant or breastfeeding women are advised to avoid this medication, and safety and efficacy have not been established for use in children. In the case of overdose, immediate consultation with medical personnel is necessary, and careful monitoring of heart and respiratory status is required. It is not recommended to mix this medication with other drugs for injection. Store this medication in a sealed container that prevents exposure to air or moisture, and it is preferable to keep it at a temperature between 1 and 30 degrees Celsius. This way, the medication's effectiveness can be maintained for a long time.

Side effects

  • Loss of appetite
  • gastrointestinal disorders
  • nausea
  • drowsiness
  • vomiting
  • hyperhidrosis
  • dizziness
  • tachycardia
  • palpitations
  • thirst
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  • urinary retention
  • sweating
  • pain at injection site
  • headache
  • blurred vision
  • fatigue
  • irritability
  • sleep disturbances
  • insomnia
  • excitement
  • hypersensitivity
  • hallucinations
  • abuse
  • drug dependence
  • seizures
  • urticaria
  • angioedema
  • anaphylactic shock
  • pink urine
  • pallor

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is advisable to store it at room temperature between 1 and 30 degrees Celsius. This way, the medication's effectiveness can be maintained for an extended period.

Appearance and packaging

Appearance

A transparent glass ampoule containing a colorless, transparent, odorless liquid.

Package unit

2mL × 10 ampoules, 4mL × 10 ampoules, 10mL × 10 ampoules

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.