Neosiderm Ointment (Sodium Fusidate)

Key information summary

Efficacy & effects

This medication is effective against Staphylococcus and is used for osteomyelitis, sepsis, endocarditis, cystic fibrosis, bronchopneumonia, wound infections, and skin infections. In ointment form, it has antibacterial effects not only against Staphylococcus but also against Streptococcus, Corynebacterium, and Clostridium, and is used for the treatment of impetigo (pyoderma, infectious eczematous dermatitis, acne vulgaris), folliculitis, furuncles, purulent hidradenitis, and secondary infections caused by burns and trauma. The dressing form is also effective against Staphylococcus and is used for the treatment of secondary infections due to impetigo, burns, trauma, and surgical wounds. Thus, this drug helps in the treatment of skin and soft tissue infections and various serious infectious diseases.

Dosage

Tablets: Administer 1-1.5 g (potency) of fusidic acid orally in 2-3 divided doses during meals. Ointment: Clean the affected area and apply a suitable amount directly to the affected area 1-2 times a day or spread it on sterile gauze and attach it. Avoid applying a thick layer and limit the treatment duration to about 1 week. Dressing: Clean the affected area, remove the paper, and apply one dressing directly to the affected area per day. Cover it.

Precautions

This drug should not be used in patients who are allergic to fusidic acid and its salts. Additionally, it should be avoided in patients with urinary tract Staphylococcus infections that are not due to kidney disease. Patients with liver dysfunction should use this drug with caution, and liver function tests should be performed regularly during long-term or high-dose administration. Gastrointestinal symptoms such as nausea, vomiting, diarrhea, loss of appetite, and abdominal pain may occur when using this drug, so caution is advised. It can affect the blood, resulting in symptoms such as granulocytopenia, thrombocytopenia, and bone marrow suppression; therefore, any unusual symptoms should be reported immediately. Rarely, prolonged high-dose use may cause jaundice, in which case the dosage should be reduced. Allergic reactions, such as skin rashes, may occur occasionally, so monitoring skin condition is essential. To prevent the development of resistant bacteria, it is recommended to conduct susceptibility testing and use it only for the minimum necessary duration. This drug is primarily excreted through bile, so dose adjustment is not necessary in patients with poor kidney function. When used in combination with other medications, interactions may occur, particularly with anticoagulants, statins, and HIV treatments, so consulting a physician is advisable. Pregnant women or those who may become pregnant should use this drug only when the benefits exceed the risks, as it can cross the placenta. Breastfeeding women should stop nursing and use this drug cautiously, as it can be transmitted through breast milk. Newborns or premature infants may have immature liver function, so liver function should be carefully monitored during use. In cases of overdose, symptoms such as liver dysfunction, jaundice, abdominal discomfort, and diarrhea may occur; treatment should be symptomatic, and dialysis is not recommended. When used topically, if there is any hypersensitivity reaction, rash, itching, etc., it should be stopped immediately, and it is better not to apply it to the eyes or eyelids. Care should be taken when applying over long periods or large areas, as resistant bacteria may develop, and appropriate treatment is necessary should microbial dysbiosis occur.

Side effects

Granulocytopenia, thrombocytopenia, bone marrow suppression, jaundice, liver dysfunction

Alternatives / Same-ingredient medications

• Fusidin Ointment (Sodium Fusidate)

  Same ingredient
• Fusimed Ointment (Sodium Fusidate)

  Same ingredient
• Parason Ointment (Sodium Fusidate)

  Same ingredient
• Samik Sodium Fusidate Ointment

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