Chungwoo 10% Dextrose Injection

Key information summary

Efficacy & effects

This medication helps provide energy in patients with hyperkalemia, circulatory collapse, and hypoglycemia. It is also used to supply fluids and energy during treatment for heart disease. It is used to support recovery in cases of drug or poison overdose. Additionally, it is effective for overall fluid and energy replenishment, thus assisting in various conditions. Therefore, this medication is used for hyperkalemia, circulatory collapse, hypoglycemia, heart disease treatment, and poison overdose.

Dosage

Administer intravenously 20 to 500 mL at a time. The infusion rate should not exceed 0.5 g/kg of glucose per hour. Use an appropriate amount for dilution of the injectable solution. Adjust as necessary based on age and symptoms.

Precautions

This medication should be handled very carefully when cutting the ampoule, as glass fragments may be introduced, especially when administered to children and the elderly. This medication, which contains glucose, may increase the consumption of vitamin B1 (thiamine) when administered via intravenous injection, potentially leading to severe deficiency. This medication should not be administered to patients with certain conditions such as storage dehydration, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucosuria, anuria, hepatic coma, etc. Additionally, this medication in hypertonic form should not be used in patients with spinal hemorrhage, intracranial hemorrhage, or delirium tremens. Administration should be undertaken with caution in patients prone to deficiencies of potassium, phosphate, magnesium, as well as in those with hyponatremia, diabetes insipidus, renal failure, heart failure, severe malnutrition, thiamine deficiency, sepsis, or severe trauma. Rapid or excessive administration of this medication may cause electrolyte imbalance and fluid overload, and exceeding the recommended dosage may elevate serum bilirubin and lactate levels. Care should be taken as complications such as fluid and electrolyte imbalance, congestion, and pulmonary edema may occur during intravenous administration. In diabetic patients or those with glucose intolerance, hyperglycemia and renal loss may occur. Long-term administration may affect insulin secretion, so insulin therapy should be combined if necessary. In patients with glucose intolerance following surgery or trauma, it is safer to administer a 5% solution under blood glucose control. Regular serum electrolyte tests, fluid balance, and blood glucose concentration monitoring are essential, and the patient’s condition and various blood test values should be carefully observed. During pregnancy, this medication should only be administered when the therapeutic benefits outweigh potential risks as safety for the fetus has not been established. When administered during labor, both mother and newborn may experience metabolic anomalies such as hyperglycemia or hypoglycemia, thus careful consideration is required. Newborns, especially preterm or low-birth-weight infants, are at higher risk of hypoglycemia and hyperglycemia, necessitating close monitoring of blood glucose levels. Elderly patients may have decreased physiological function, thus requiring more caution during administration. In cases of overdose where symptoms of hyperglycemia or diabetes appear, insulin administration should be utilized for control. Subcutaneous injections should be avoided as they may cause local irritation and circulatory failure; any remaining medication should be discarded immediately after opening. To reduce the risk of infection during injection, attention to hygiene is essential, and it is advisable to warm the medication to body temperature before administration. Sudden discontinuation following the administration of concentrated solutions may lead to hypoglycemia, so caution is advised. When mixed with other medications, there is a risk of chemical and physical adverse effects, hence thorough understanding and observation are necessary. Additionally, to minimize the risk of air embolism in the container, it is preferable not to use continuous connections.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice of the skin or eyes, generalized lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, marked reduction in urine output, generalized

Alternatives / Same-ingredient medications

• Jungwoo 5% Glucose Injection

  Same ingredient
• Jungwoo 20% Glucose Injection

  Same ingredient
• Jungwoo 50% Glucose Injection

  Same ingredient
• Daehan Glucose Injection (10%)

  Same ingredient

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