Vancocin Injection 0.5g (Vancomycin Hydrochloride)

Adult dosage

As Vancomycin, intravenously administer 500mg every 6 hours or 1g every 12 hours. When administered orally, it is generally given as 500-2000mg daily in 3-4 divided doses for 7-10 days, with a total daily dose exceeding 2g not recommended.

Children's dosage

For children, intravenously inject 10mg per kg of body weight every 6 hours. For infants, intravenously inject 10-15mg per kg of body weight every 12 hours. For infants and newborns, an initial dose of 1

This medication should not be used in patients who have previously experienced severe allergic reactions or shock due to this medication. Additionally, it should not be administered to patients allergic to this medication or certain antibiotics. Caution should be exercised when administering to patients with hearing loss or renal dysfunction, particularly those who have previously experienced auditory damage from similar classes of drugs. Patients with liver function impairment, elderly patients, preterm infants, and neonates also require careful monitoring. Rarely, neurological symptoms, gastrointestinal symptoms, decreased blood cell counts, and central nervous system symptoms may occur during administration, and if any abnormal symptoms arise, they should be reported immediately. Regular blood tests and liver and kidney function tests are necessary as this medication may affect liver and kidney function. Serious skin rashes or inflammation may occur, so skin condition should be closely monitored. Rapid infusion may result in redness or pain in the face, neck, and trunk, as well as muscle cramps, so it is important to infuse slowly. Prolonged use of this medication may lead to overgrowth of certain bacteria, so if diarrhea or abdominal pain occurs, administration should be discontinued immediately and appropriate treatment should be sought. Interactions may occur when used with other medications, particularly with drugs that may cause neurotoxicity or nephrotoxicity, so careful observation is required. When used with anticoagulants, frequent tests of blood coagulation status may be necessary for dosage adjustment. Women who are pregnant or breastfeeding should consult a doctor before administration, as this medication may affect the fetus or newborn. If breastfeeding, it is advisable to avoid use and, if necessary, to discontinue breastfeeding. Pediatric patients, especially preterm infants and neonates, may have immature renal function that can result in higher drug levels, so careful use is required. Overdose may result in renal dysfunction or hearing impairment, requiring careful attention and appropriate treatment and monitoring. This medication must be administered intravenously; intramuscular injection or careless administration may cause tissue damage or necrosis. The infusion rate should be slow, allowing at least 60 minutes for infusion, as rapid administration can increase the risk of hypotension or cardiac arrest. Before administration, visually check for discoloration or the presence of particulate matter, and take care to avoid chemical instability when mixing with other medications. Prolonged use of this medication may lead to the development of resistant bacteria, so use it only for the necessary minimum duration and based on sensitivity testing.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough+fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, altered consciousness, visual disturbances, paralysis, urine.

Mild side effects

• Loose stools
• diarrhea
• nausea
• vomiting
• abdominal pain
• decrease in red blood cells
• decrease in white blood cells
• decrease in platelets
• increase in eosinophils
• dizziness

This medication should be stored in a sealed container to prevent air or moisture from entering, at a temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and allow for safe usage.

Appearance

A white or light brown freeze-dried powder in a colorless transparent vial for injection.

Package unit

Vial - 10 vials/box [(0.5g/vial) x 10]