Rosuvam 5mg (Rosuvastatin Calcium)

Adult dosage

This medication can be taken at any time of the day, regardless of meals. The initial dose is 5 mg once daily. The maintenance dose is usually 10 mg once daily, with most patients adjusted to this dose. The maintenance dose should be adjusted based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum daily dosage of 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the typical dosage range is 5 mg to 20 mg once daily. The dosage should be adjusted according to each patient's treatment goals.

This drug should not be used in certain patients. For example, individuals allergic to this medication, those with severe liver impairment, or those with muscle-related diseases should avoid it. Additionally, special caution is required for pregnant or breastfeeding women and women of childbearing age who are not using appropriate contraception; it should only be used if there is assurance of low pregnancy probability. Care should be taken when prescribing high doses to patients with a history of muscle disease or moderate to severe renal impairment due to the risk of muscle damage. Patients with genetic disorders that prevent lactose digestion should also avoid this medication. Patients with liver dysfunction or those consuming excessive alcohol should undergo regular liver enzyme tests and use the medication cautiously. If muscle pain or weakness occurs, patients should inform their doctor immediately, and in severe cases, they may need to stop the medication. Special monitoring is necessary prior to and after treatment in elderly patients, those with reduced kidney function, or those with hypothyroidism who have risk factors for muscle damage. The use of this drug should be temporarily suspended when acute severe illness occurs. This medication can rarely induce severe muscle weakness or ocular muscle weakness; if such symptoms appear, it should be stopped immediately. When used with certain other medications, the risk of muscle damage may increase; therefore, consult with a doctor about any concomitant medications. High-dose administration may result in transient kidney proteinuria, so it is advisable to undergo regular kidney function tests. Asian patients may exhibit higher drug concentrations, thus requiring dose adjustments. Pediatric and adolescent patients should be considered for their effects on growth and development. This medication has been reported to cause various adverse reactions such as liver dysfunction, increased risk of diabetes, and severe skin reactions; thus, immediate consultation with medical staff is necessary if symptoms arise. This medication should not be used during pregnancy or breastfeeding, and women planning a pregnancy should use appropriate contraceptive methods. There is no specific antidote for overdose, so treatment should be symptomatic and include liver function and muscle enzyme tests. Caution is advised when driving or operating machinery, as dizziness may occur. It is essential to consult with a doctor and undergo regular check-ups to ensure the safe use of this medication.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, eosinophilia with systemic symptoms and drug reaction with eosinophilia and systemic symptoms, rhabdomyolysis, severe muscle weakness, ocular muscle weakness, dyspnea, interstitial lung disease, jaundice, fatal and non-fatal liver failure, acute renal failure, oliguria, severe edema, thrombocytopenia, severe allergic reactions, severe skin reactions, respiratory problems, liver abnormalities (jaundice), serious kidney issues

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, rash, muscle pain, weakness, hematuria, diarrhea, chest discomfort, loss of appetite, abdominal bloating, fatigue, numbness, paraesthesia, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, joint pain, amnesia, peripheral neuropathy, thrombocytopenia, transaminase elevation, hepatitis, eosinophilia, drug reaction with eosinophilia and systemic symptoms, lupus-like syndrome, immune-mediated necrosis

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and it is best stored at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication and prevent deterioration.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets (15 tablets/PTP x 2 packs)