Medication info
Pregalin Capsule 75 mg (Pregabalin)

Pregalin Capsule 75 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›75mg / 1 capsule
Manufacturer / importer
(주)킵스바이오파마
Appearance
Hard capsule with a reddish-brown upper part and a white lower part containing a white or light yellow powder
Packaging
100 capsules/bottle, 30 capsules/bottle
Approval status
Active

MFDS item code 202001235 · Approved 2020.02.21 · Insurance code 629701960,693202640

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial onset seizures, relief of fibromyalgia
Who takes it
Adults · Children
Adult dose
This medication is administered orally in divided doses twice daily without regard to meals. 1. Neuropathic pain - Peripheral neuropathic pain: Start with a dose of 150 mg once daily, which can be increased to 300 mg after 3 to 7 days, and then further increased to a maximum of 600 mg over a period of 7 days. - Central neuropathic pain: Start with a dose of 150 mg once daily, which can be increased to 300 mg after 1 week.
Child dose
Safety and effectiveness data for pediatric patients under 12 years of age and adolescents aged 12 to 17 is insufficient, therefore administration is not recommended.

Ingredients

Manufacturer
(주)킵스바이오파마

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial onset seizures, relief of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures with or without secondary generalized symptoms
  • fibromyalgia
View approved original text

This medication is used to treat peripheral and central neuropathic pain in adults. It is also utilized as an adjunctive therapy for patients with epilepsy who have partial seizures, applicable in cases with or without secondary generalized symptoms. Additionally, it helps alleviate the symptoms of fibromyalgia. It is effectively used for various neurological conditions and pain states.

How to take

Adult dose

This medication is administered orally in divided doses twice daily without regard to meals. 1. Neuropathic pain - Peripheral neuropathic pain: Start with a dose of 150 mg once daily, which can be increased to 300 mg after 3 to 7 days, and then further increased to a maximum of 600 mg over a period of 7 days. - Central neuropathic pain: Start with a dose of 150 mg once daily, which can be increased to 300 mg after 1 week.

Child dose

Safety and effectiveness data for pediatric patients under 12 years of age and adolescents aged 12 to 17 is insufficient, therefore administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so if you experience mood changes or unusual behavior during treatment, you must inform your healthcare provider immediately. Patients who are allergic to any components of this drug or have a hereditary lactose intolerance should not take this medication. Diabetic patients should be cautious as weight gain may require adjustments to blood sugar control medications. If symptoms of angioedema occur, the medication should be discontinued immediately. Elderly patients may experience dizziness or drowsiness, increasing the risk of falls, and should be cautious until they become accustomed to the effects of this drug. Temporary blurred vision or changes in vision may occur, which can improve upon discontinuation of the medication. Abruptly stopping this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so it should be discontinued gradually under a doctor's guidance. Patients with a history of substance abuse may be at a higher risk for misuse of this medication and require special caution. Dose adjustments may be necessary for patients with impaired kidney function. Patients with heart disease should be cautious while taking this medication as symptoms of heart failure may occur. When taken with opioid analgesics, the risk of central nervous system depression is increased, so consult with a healthcare provider. This medication may cause dizziness and drowsiness, so caution is advised when driving or operating machinery. In early pregnancy, there is a risk of fetal malformation, so pregnant women should not take this medication, and women of childbearing age should use effective contraception. During breastfeeding, this drug can be transmitted to breast milk and may affect infants, so one should either stop breastfeeding or consult a doctor. In cases of overdose, symptoms such as confusion, drowsiness, and seizures may appear, and treatments such as hemodialysis may be required. Keep this medication out of reach of children, and do not transfer it into other containers. If a skin rash or a severe allergic reaction occurs while taking this medication, discontinue use immediately and inform your healthcare provider.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rashes with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy throughout the body, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • loss of direction
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • sexual hyperesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional lowering
  • emotional elevation
  • difficulty finding appropriate words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • loss of inhibition
  • apathy
  • ataxia
  • motor coordination difficulty
  • balance disorder
  • amnesia
  • attention disturbance
  • memory impairment
  • tremors
  • dysarthria
  • sensory disturbances
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to protect it from air and moisture, and keep it at room temperature between 15 to 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness for a longer period.

Appearance and packaging

Appearance

Hard capsule with a reddish-brown upper part and a white lower part containing a white or light yellow powder

Package unit

100 capsules/bottle, 30 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.