Il Sung Fluconazole Capsule 150 mg

Adult dose

The route of administration should be determined according to the patient's clinical condition. Oral formulations are absorbed rapidly and almost completely; therefore, the doses of oral formulations (tablets, capsules, dry syrup) and injectable formulations are the same. ○ Adults 1. Vaginal candidiasis: Administer fluconazole 150 mg orally as a single dose. 2. Systemic candidiasis, including candidemia, disseminated candidiasis, and other invasive Candida infections (peritoneal, endocardial, pulmonary, urinary tract, etc.): The usual dose of this medicine is 400mg once on the first day, followed by 200mg once daily from the next day; the dose may be increased to 400mg once daily according to the patient's response. The duration of treatment is determined according to clinical response and medical judgment. 3. Cryptococcal meningitis and cryptococcosis at other sites: The usual dose of this medicine is 400mg once on the first day, followed by 200 ~ 400mg once daily from the next day. The duration of treatment is determined by clinical and mycological response, but treatment should generally be continued for at least 6 ~ 8 weeks. 4. To prevent recurrence of cryptococcal meningitis in patients with AIDS, administer 200mg of this medicine once daily indefinitely after the patient has completed primary treatment. 5. Prevention of fungal infections in immunocompromised patients at risk due to neutropenia caused by cytotoxic chemotherapy, radiation therapy, or bone marrow transplantation: Administer 50~ 400mg of this medicine once daily, depending on the patient's risk of fungal infection. A dose of 400mg once daily is recommended for patients at very high risk of systemic fungal infection, such as those undergoing bone marrow transplantation, in whom severe or prolonged neutropenia is expected. In these patients, administer 400mg starting 5-6 days before the expected onset of neutropenia, and continue administering 400 mg for 1 week after the neutrophil count has increased to 1,000cells/mm3 or higher. 6. For onychomycosis, administer 150 mg once weekly until the fingernails or toenails have regrown (until new, uninfected nails have grown). New fingernails usually take 3-6 months to grow, and toenails take 6-12 months; growth rates may vary among individuals and with age. Even after successful treatment with long-term administration, the fingernails or toenails may sometimes remain damaged. For fungal skin infections, including athlete's foot (tinea pedis), tinea corporis, tinea cruris, and cutaneous candidiasis: The usual dose of this medicine is 50 mg once daily or 150 mg once weekly for 2-4 weeks. However, athlete's foot may require treatment for 6 weeks, depending on the course of the condition. For tinea versicolor, administer 50mg once daily for 2-4 weeks. ○ Older adults If renal function is normal, the usual adult dose is generally administered. In patients with renal impairment (creatinine clearance 50 ml/min or less), the dose should be reduced or the dosing interval extended. ○ Patients with renal impairment This medicine is excreted mainly in the urine unchanged. No dosage adjustment is necessary for a single dose, but if multiple doses are required, administer the usual dose only on the first day and adjust the dose from the following day as follows. Creatinine clearance (mL/min) > 50: 100 % of the usual dose Creatinine clearance (mL/min) ≤ 50 (not on dialysis): 50% of the usual dose Patients on regular dialysis: 100% of the usual dose after each hemodialysis session Patients receiving hemodialysis should receive 100% of the usual dose after each hemodialysis session; on days when dialysis is not performed, reduce the dose according to creatinine clearance.

This medication should not be administered to certain patients. For example, patients who have had allergic reactions to this medication or similar drugs, pregnant women or those who may become pregnant, nursing mothers, and patients taking certain medications should not use this drug. This drug contains lactose, so it should not be given to patients with lactose intolerance or related genetic conditions. Use this drug with caution in patients with impaired renal or liver function, those with heart disease or at risk of arrhythmia, and patients with a history of drug allergies. The condition of these patients should be closely monitored during treatment. This drug may interact with various medications, so if you are taking other medications, you must consult with your healthcare provider. Special caution is required when taken with medications that affect the heart, drugs metabolized by the liver, anticoagulants, immunosuppressants, and antidepressants. While this medication is generally well tolerated, it can rarely cause adverse effects such as abnormalities in blood, liver, or kidney function, serious skin reactions, or cardiac arrhythmias. If any unusual symptoms occur, notify your healthcare provider immediately. Its use during pregnancy could pose a risk to the fetus, so it should be avoided whenever possible, and fertile women should use effective contraception during and after treatment for a certain period. Nursing mothers are also advised against using this medication. The safety of this drug in children, particularly infants under 6 months old, has not been fully established, so it should only be used cautiously when necessary. Caution is needed when driving or operating machinery after taking this medication as dizziness or seizures may occur. In cases of overdose, hallucinations or abnormal behavior may occur, and appropriate treatment should be sought immediately. This drug is primarily excreted in the urine, so measures to increase urine output may be helpful in the event of overdose.

Agranulocytosis, leukopenia, neutropenia, thrombocytopenia, anaphylaxis, angioedema, hypertriglyceridemia, hypercholesterolemia, hypokalemia, insomnia, drowsiness, headache, seizures, dizziness, sensory disturbances, taste disturbances, tremor, vertigo, Torsade de pointes, QT prolongation, abdominal pain, diarrhea, nausea, vomiting, dyspepsia, abdominal distension, dry mouth, increased ALT, increased AST, elevated serum alkaline phosphatase, cholestasis, jaundice, increased bilirubin, hepatotoxicity, hepatic failure, hepatocellular necrosis, hepatitis, hepatocellular damage, rash, itching, urticaria, increased sweating, drug rash, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, exfoliative dermatitis, facial edema, alopecia, drug reaction with eosinophilia and systemic symptoms, myalgia, fatigue, malaise, asthenia, fever, adrenal insufficiency, hallucinations, psychotic behavior

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius to preserve its effectiveness for a longer period.

Appearance

Capsule filled with white powder, upper dark blue and lower light blue

Package unit

30 capsules/bottle