Carvedilol Tablets 12.5 mg (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor’s instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may be sufficiently effective. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient’s existing standard treatment regimen (the conventional treatment regimen for chronic heart failure, consisting of an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial treatment is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be administered to certain patients. For instance, it may be dangerous for those with allergies to this medication or its components, cardiac shock, heart conduction disturbances, cor pulmonale, diabetic ketoacidosis, severely impaired cardiac function, asthma, or chronic lung disease. It is also advisable for pregnant or breastfeeding women not to use this medication. Patients with genetic issues such as lactose intolerance should also avoid taking it. Care should be taken with patients who have diabetes, a history of hypersensitivity, heart disease, impaired kidney or liver function, elderly patients, etc., as there may be an increased potential for symptom worsening or side effects. The medication should be taken carefully under the guidance of a physician. This medication may cause various side effects such as dizziness, headache, fatigue, reduced heart rate, lowered blood pressure, worsening heart failure, gastrointestinal symptoms, skin rashes, etc. If any abnormal symptoms occur, immediate consultation with medical personnel is necessary. Regular monitoring of cardiac function tests, blood pressure, pulse, liver and kidney functions is important when taken long-term. Suddenly stopping the medication may worsen symptoms, so the dose should be gradually reduced according to a physician's instructions. This medication may interact with other drugs, so care should be taken particularly when taken together with antihypertensives, antidepressants, antiarrhythmics, insulin, alcohol, etc. All medications being taken should be disclosed to the doctor or pharmacist. Pregnant or breastfeeding individuals should not take this medication, and its safety in children and adolescents has not been established, so its use is not recommended. In case of overdose, severe symptoms such as pronounced hypotension, decreased heart rate, heart failure, and respiratory distress may occur, and immediate contact with medical institutions is necessary for appropriate treatment. This medication may discolor due to light, so it should be stored in a sealed container that blocks light, kept away from direct sunlight, and stored out of reach of children, without being transferred to another container.

• Dizziness
• headache
• fatigue
• weakness
• hallucination
• confusion
• depression
• sleep disorder
• nightmares
• mental illness

This medication should be stored in a sealed container that can block light and kept at room temperature between 1 to 30 degrees Celsius. Storing it this way will maintain the effectiveness of the medication and prevent degradation.

Appearance

Reddish-brown round tablets

Package unit

90 tablets (10 tablets/PTP X 9)