Clamoxen Neo Syrup (Amoxicillin-Potassium Clavulanate (14:1))

Child dose

For pediatric patients over 3 months: Based on the amoxicillin content (600 mg/5 mL), take 90 mg/kg/day divided into two doses every 12 hours. For acute otitis media, treat for 10 days; for acute sinusitis, treat for 7 days.

This medication contains the artificial sweetener aspartame, which breaks down into phenylalanine in the body. Hence, it should not be used in patients with the genetic disorder phenylketonuria. The daily intake of aspartame in this medication should be managed to not exceed the recommended daily amount by WHO, and for a 60 kg adult, it should not exceed a maximum of 2.4 g per day. Caution should be exercised when administering this medication to patients with known allergies to its components or beta-lactam antibiotics, those with infectious mononucleosis or lymphocytic leukemia, those with a history of liver dysfunction or jaundice, and those with lactose intolerance or other genetic issues. Patients with impaired liver function or severe renal disease should use this medication cautiously, and those with allergic tendencies, older adults, or those in poor general condition may be at risk for vitamin K deficiency and should be monitored closely. This medication may cause gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain, and in rare cases, liver disease such as hepatitis or cholestatic jaundice may occur. Symptoms of liver dysfunction may arise during or after treatment, so careful observation is necessary. Furthermore, severe allergic reactions such as rash, urticaria, Stevens-Johnson syndrome, or others may appear, and any unusual symptoms should prompt immediate discontinuation and consultation with a physician. Blood abnormalities may also occur infrequently, and neurological symptoms such as dizziness, headaches, and seizures have been reported, so caution should be taken if these symptoms appear. This medication can affect kidney function; hence, patients with renal impairment should undergo regular testing, and in cases of overdose, gastrointestinal symptoms such as vomiting, diarrhea, and abdominal pain may accompany the risk of kidney damage, necessitating proper hydration and management. This medication may interact with other drugs, so patients taking anticoagulants, certain antibiotics, anti-inflammatory drugs, etc., should definitely inform their doctor. Women who are pregnant or nursing should weigh the risks and benefits when using this medication, especially avoiding use during the first trimester of pregnancy. This medicine should not be used in infants under 3 months as safety and efficacy have not been established. Lastly, this medication is ineffective for viral infections and should only be used for treating bacterial infections, and it must be taken exactly as prescribed regarding the duration and dosage. The medication should be shaken well before use and stored in the refrigerator after preparation and used within 7 days.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by fever, blistering, skin peeling, pain in oral/ocular mucosa, wheezing or difficulty breathing, asthma attack, respiratory distress with cough and fever, jaundice or yellowing of skin/eyes, a feeling of extreme fatigue throughout the body, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

Contact dermatitis, diarrhea, vomiting, moniliasis, rash, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, loss of appetite, abdominal pain, abdominal distension, constipation, colonic pain, hyperacidity, melena, dry mouth, elevated liver enzymes (AST, ALT, ALP, LDH, serum bilirubin), hepatitis, cholestatic jaundice, itching, erythema multiforme, serum sickness symptoms, hypersensitivity vasculitis, acute generalized exanthematous pustulosis

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. Additionally, it must be kept in a cool and dry place between 1 to 25 degrees Celsius to maintain its efficacy.

Appearance

A syrup that dissolves in water with a peculiar odor, in the form of a white to pale yellow powder

Package unit

50 milliliters/bottle