Medication info
Lyrica CR Controlled-Release Tablet 82.5 mg (Pregabalin)

Lyrica CR Controlled-Release Tablet 82.5 mg (Pregabalin)

Prescription medicationTablet경구
Ingredient · strength
Pregabalin›82.5mg / 1 tablet
Manufacturer / importer
비아트리스코리아(주)
Appearance
Bright blue almond-shaped film-coated controlled-release tablet
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 201802989 · Approved 2018.07.18 · Insurance code 073400250

Summary

Main use
Relief of peripheral neuropathic pain
Who takes it
Adults · Children
Adult dose
This medication should be taken once daily after the evening meal. It should be swallowed whole and not divided, crushed, or chewed. The starting dose is 165 mg once daily, and it can be increased to 330 mg once daily after 3 to 7 days. If necessary, it can be further increased to a maximum of 660 mg once daily at 7-day intervals. Patients with decreased kidney function should adjust the dose based on creatinine clearance. For children aged 12 years and above, the same guidelines apply.
Child dose
The safety and efficacy data are insufficient for children under 12 years of age and adolescents aged 12-17, so its use is not recommended.

Ingredients

Importer
비아트리스코리아(주)

Efficacy & effects

Relief of peripheral neuropathic pain

  • Peripheral neuropathic pain
View approved original text

This medication is used to relieve pain arising from peripheral neuropathy in adult patients. Peripheral neuropathic pain refers to pain caused by nerve damage, and this medication effectively alleviates such neuropathic pain.

How to take

Adult dose

This medication should be taken once daily after the evening meal. It should be swallowed whole and not divided, crushed, or chewed. The starting dose is 165 mg once daily, and it can be increased to 330 mg once daily after 3 to 7 days. If necessary, it can be further increased to a maximum of 660 mg once daily at 7-day intervals. Patients with decreased kidney function should adjust the dose based on creatinine clearance. For children aged 12 years and above, the same guidelines apply.

Child dose

The safety and efficacy data are insufficient for children under 12 years of age and adolescents aged 12-17, so its use is not recommended.

Precautions

This medication is a type of anticonvulsant and is used in the treatment of neuropathic pain and peripheral neuropathic pain. Patients taking this medication should be closely monitored for suicidal thoughts or behaviors, depressive symptoms, and mood changes. If any of these mental changes occur during medication, it is essential to inform healthcare professionals immediately. Patients with allergies to pregabalin or any components of this medication should not take it. Diabetics may experience weight gain due to this medication, which may require adjustments in blood sugar control medications. If any allergic reactions, such as angioedema, appear, discontinue use immediately and consult healthcare professionals. Elderly patients may experience symptoms such as dizziness, drowsiness, or confusion when taking this medication, so caution is necessary during initial use. This medication may cause blurred vision or changes in eyesight; these symptoms may improve after discontinuing the medication. Patients with a history of substance abuse may have an increased risk of dependence on this medication, so caution is advised during use. Patients with decreased kidney function should have their dose adjusted, and this medication is not recommended for patients on dialysis. Patients with heart disease should use this medication cautiously, as it may increase the risk of congestive heart failure. Taking this medication with opioid analgesics may increase central nervous system depressant effects, so caution is advised. In early pregnancy, using this medication may affect the fetus, so pregnant women should consult their doctor before use. Lactating women should consider discontinuing breastfeeding or this medication, as it may be transmitted through breast milk. Common side effects during use include dizziness, drowsiness, nausea, dry mouth, swelling, etc., and if symptoms are severe, consultation with a doctor is necessary. Caution is required when driving or operating machinery, and patients should assess their condition before engaging in these activities. In cases of overdose, symptoms such as altered consciousness, depression, agitation, seizures, etc., can occur, hence immediate emergency treatment is required. Keep out of children's reach and do not transfer to other containers for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema (facial, periorbital, and upper airway edema), loss of consciousness, mental disorders, Stevens-Johnson syndrome, toxic epidermal necrolysis, symptoms similar to anaphylaxis, liver abnormalities (symptoms related to jaundice), severe swelling, paralysis (facial paralysis), pulmonary edema, congestive heart failure, shock, deep vein thrombosis, atrial fibrillation, thalamic stroke, severe allergic reactions, serious neurological symptoms, respiratory issues, severe skin adverse reactions,

Mild side effects

Dizziness, drowsiness, headache, nausea, vomiting, diarrhea, constipation, dry mouth, fatigue, weight gain, blurred vision, diplopia, back pain, joint pain, contact dermatitis, rash, hives, increased appetite, insomnia, erectile dysfunction, cough, rhinitis, urinary tract infection, upper respiratory infection, bronchitis, viral respiratory infection, sinusitis, viral gastroenteritis, alanine aminotransferase (ALT) increase, aspartate aminotransferase (AST) increase,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air or moisture. It is best kept at room temperature between 1°C and 30°C. Maintaining this temperature range preserves the drug's efficacy and safety.

Appearance and packaging

Appearance

Bright blue almond-shaped film-coated controlled-release tablet

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.