Levisin 500 mg (Levofloxacin Hemihydrate)

Adult dose

For adults, Levofloxacin is administered orally once daily at a dose of 250 to 750 mg. In patients with normal renal function, based on indications, doses of 250 mg to 750 mg are administered at 24-hour intervals, and the treatment duration varies from 3 to 28 days depending on the site of infection. In patients with renal impairment, dosage and administration intervals are adjusted according to creatinine clearance. For example, in the case of complicated skin and soft tissue infections, the creatinine clearance

This drug is a fluoroquinolone antibiotic used for the treatment of infections. This drug can cause serious side effects such as tendonitis or tendon rupture, and if such symptoms appear, it should be discontinued immediately. It is not used in patients with myasthenia gravis as symptoms may worsen. Additionally, this drug is recommended to be used only when there are no other treatment options for specific acute bacterial infections. Caution is needed as the risk of tendon rupture is higher in the elderly, patients with decreased renal function, and those taking corticosteroids together. If pain or inflammation occurs during exercise, it should be discontinued immediately and rest taken. Patients with myasthenia gravis should be careful as this drug can have neuromuscular blocking effects that may worsen symptoms. This drug should not be used in patients who: Are allergic to quinolone antibiotics or have a history of tendonitis or tendon rupture, adolescents under 18 years of age, pregnant or breastfeeding women, have epilepsy, or have lactose intolerance. Particularly in patients with severely impaired renal function, central nervous system diseases, a history of seizures, those taking certain anti-inflammatory medications or theophylline, diabetic patients, and patients with blood disorders, this drug should be used with caution. While taking this medication, serious allergic reactions, psychiatric symptoms, cardiac arrhythmias, liver or kidney dysfunction, blood disorders, gastrointestinal disturbances, muscle and joint problems, skin reactions may occur seldom, so consult a doctor immediately if unusual symptoms appear. This drug may interact with other medications, so especially when taking anti-inflammatory medications, antacids, iron supplements, calcium supplements, hypoglycemic agents, anticoagulants together, it is recommended to consult a specialist. Pregnant or breastfeeding women should not take this drug, and breastfeeding should be discontinued while on this medication. Safety has not been established for children and adolescents in growth, so it is not used. Elderly patients may have prolonged drug retention due to decreased kidney function, increasing the risk of side effects, so dosage adjustment and caution are necessary. In case of overdose, central nervous system symptoms and cardiac abnormalities may occur, and immediate treatment at a hospital is required, as this drug is not removed by hemodialysis. During the use of this drug, excessive exposure to sunlight or artificial ultraviolet light should be avoided, and caution should be taken when driving or operating machinery as dizziness or drowsiness may occur.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• hypotension
• dyspnea
• chest pressure
• shock

Mild side effects

Insomnia, dizziness, headache, tremors, anxiety, depression, psychiatric reactions (hallucinations, paranoia, nervousness, delirium, disorientation, attention deficit, nightmares, sleep disorders, suicidal thoughts, etc.), restlessness, confusion, visual and auditory disturbances, taste and smell disorders, auditory hallucinations, mania, sensory disturbances, sensory loss, sensory disorders, weakness, palpitations, QT interval prolongation, arrhythmia, elevated BUN and serum creatinine, nausea, vomiting, abdominal discomfort

This drug may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is advised to store it in a normal temperature, i.e., between 1 to 30 degrees Celsius, not in overly hot or cold places.

Appearance

Pink rectangular film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle