Crosstin 5 mg (Rosuvastatin Calcium)

Adult dosage

Administer 5 mg once daily as initial dosage, regardless of meal timing. If a greater reduction in LDL cholesterol is needed, titrate to maintenance dosage, usually adjusted to 10 mg once daily. The maintenance dosage should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), administer 5 mg to 20 mg once daily. The dosing should be tailored according to individual patient treatment goals every 4 weeks or more.

This medication should not be used in certain patients. For instance, those allergic to the components of this medication, individuals with severe liver impairment, patients with muscle disorders, and those taking certain medications should not take this drug. Women who are pregnant or breastfeeding, as well as fertile women who are not using appropriate contraceptive methods, should consult a physician before taking this medication and may only take it if it is understood that the risk to the fetus is low. Caution is advised for patients with liver disease or those who consume alcohol excessively, and regular liver function tests should be conducted. Additionally, if symptoms such as muscle pain or muscle weakness occur, the physician should be notified immediately. Patients with various factors that may increase the risk of muscle damage, such as renal impairment, hypothyroidism, a history of hereditary muscle diseases, alcohol abuse, and concomitant use of certain medications, should be monitored more closely. This drug contains lactose, so patients with lactose intolerance should avoid taking it. During treatment with this drug, liver function and muscle condition should be regularly checked, and any unusual symptoms should be reported to healthcare professionals immediately. This drug may interact with other medications; therefore, patients should inform their doctor or pharmacist about any other medications they are taking. Special caution is required when used with certain antiviral medications, immunosuppressants, antibiotics, and lipid-lowering agents. Pregnant or breastfeeding women should not use this medication, and women of childbearing potential should use appropriate contraception. In case of overdose, there is no specific antidote, and immediate medical attention should be sought for appropriate treatment and examination. This drug is not known to significantly affect driving or the operation of machinery; however, caution is advised due to the potential occurrence of dizziness and other symptoms. Lastly, while taking this medication, serious skin reactions, severe liver damage, and muscle-related anomalies may occur; if such symptoms are suspected, the medication should be discontinued immediately, and medical advice should be sought.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug rash with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, hyperbilirubinemia, acute kidney failure, oliguria, liver failure, severe muscle weakness, oculomotor nerve palsy, rhabdomyolysis, severe edema, dyspnea, chest tightness, fatal liver damage

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to protect it from air and moisture and should be kept at room temperature between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets (14 tablets/PTP*2), 30 tablets/bottle, 100 tablets/bottle