Huriard Tablet (Tenofovir Disoproxil)

Adult dose

Adults: For the treatment of HIV-1 or chronic hepatitis B, take 1 tablet (equivalent to 245mg of tenofovir disoproxil) once daily. It may be taken with or without food. The optimal duration of treatment for chronic hepatitis B is unknown. Patients with renal impairment: For patients with a baseline creatinine clearance of <50mL/min, adjust the dosing interval of this medicine by referring to Table 1. For patients with mild renal impairment, no adjustment to the dosing interval of this medicine is necessary (creatinine clearance 50-80mL/min); estimated creatinine clearance, serum phosphate, urine glucose, and urine protein should be monitored regularly. Creatinine clearance (mL/min) ≥50: every 24 hours Creatinine clearance (mL/min) 30-49: every 48 hours Creatinine clearance (mL/min) 10-29: every 72-96 hours Patients on hemodialysis: every 7 days or approximately 12 hours after a total of dialysis. Assuming 3 hemodialysis sessions per week, each lasting approximately 4 hours, administer once weekly. This medicine should be administered after dialysis is completed. Patients with creatinine clearance below 10mL/min who are not on hemodialysis: No dosing recommendations are available.

Child dose

Pediatric patients 12 years of age and older (35kg or more): For the treatment of HIV-1 or chronic hepatitis B, take 1 tablet once daily (equivalent to 245mg of tenofovir disoproxil). It may be taken with or without food. Pediatric patients with chronic hepatitis B weighing less than 35kg: Safety and efficacy have not been established. Pediatric patients with renal impairment: There are no data to support dosage recommendations.

Discontinuation of this medication can lead to sudden worsening of hepatitis, so regular medical check-ups should be done for several months even after stopping the medication. Do not take this medication if you are allergic to any of its ingredients or if you have certain genetic lactose intolerance disorders. This medication should not be taken with other specific antiviral agents, and you should inform your doctor about any medications you are currently taking before starting this medication. Patients with impaired kidney function or at risk of kidney disease should use this medication cautiously and have regular kidney function tests during treatment. This medication can affect bone health, so patients with bone disorders or a risk of fractures should consider discussing bone density testing with their doctor. If muscle pain or bone pain persists or worsens during treatment, consult a healthcare professional immediately. Pregnant women may use this medication if necessary, but must consult with a doctor before taking it; breastfeeding mothers should avoid breastfeeding while taking this medication. Safety and efficacy in children under 12 years of age have not been established, so it's recommended that children younger than 12 do not take this medication. Elderly patients may be affected by medications due to reduced kidney function, so close observation by a doctor is necessary while taking this medication. In case of overdose, visit a medical institution immediately for appropriate treatment, and if necessary, the drug may be removed through hemodialysis. Store this medication away from direct sunlight at room temperature between 1°C and 30°C, and keep it in a secure place out of reach of children.

• Worsening of hepatitis
• hypersensitivity
• acute renal failure
• Fanconi syndrome
• kidney impairment
• bone pain
• limb pain
• fractures
• muscle pain
• muscle weakness

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. It is recommended to maintain the storage temperature between 1°C and 30°C to retain the medication's effectiveness for a long time.

Appearance

Light blue almond-shaped film-coated tablet

Package unit

30 tablets/bottle