Preneu Capsule 150 mg (Pregabalin)

Adult dose

This medication is taken orally in two divided doses per day without regard to meals. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose is 150 mg once daily. Depending on response and tolerability, it can be increased to 300 mg once daily after 3 to 7 days, and subsequently increased to a maximum of 600 mg at intervals of 7 days. - Central neuropathic pain: Starting dose is 150 mg once daily.

Child dose

The safety and efficacy data are insufficient for patients under 12 years of age and adolescents aged 12 to 17 years; therefore, administration is not recommended.

This medication may increase the risk of suicidal thoughts or behaviors, hence careful observation for signs of depression, mood changes, or behavioral abnormalities is necessary while on treatment. Patients allergic to any ingredient of this medication should not use it. Diabetic patients may need to adjust the dosage of their blood glucose-lowering medication if weight gain occurs with this medication. If symptoms of angioedema, such as swelling of the face or around the mouth, occur, discontinue use immediately and consult a healthcare professional. Elderly individuals are at higher risk of falling or injury due to dizziness or drowsiness, so they should exercise particular caution at the start of treatment. There may be blurred vision or changes in eyesight while taking this medication; if these symptoms occur, consult a doctor. Suddenly stopping this medication may lead to withdrawal symptoms, such as insomnia, headaches, and anxiety, so adjusting the dosage according to the physician’s instruction is necessary. Due to the risk of drug abuse, patients with a history of drug abuse or psychiatric disorders should use this medication with caution. Patients with impaired kidney function may need to adjust the dosage based on their symptoms in consultation with a healthcare professional. Patients with cardiovascular diseases may experience edema or symptoms of heart failure when taking this medication, so care is required. Caution is advised when taking this medication with opioid analgesics, as it may enhance central nervous system depressant effects, leading to risks such as respiratory distress. In early pregnancy, there is a risk of fetal malformations; hence pregnant women are advised against using this medication, and women of childbearing potential should employ effective contraception during treatment. Breastfeeding women should carefully consider the effects of this medication being transmitted through breast milk on their babies. Caution is required when driving or operating hazardous machinery as this medication may cause dizziness or drowsiness. In case of overdose, symptoms such as drowsiness, confusion, and depression may occur, and immediate medical attention is necessary. This medication should be kept out of reach of children, and transferring it to another container could lead to decreased quality or accidents.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash accompanied by high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties associated with coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, decreased urine output

Mild side effects

• Dizziness
• drowsiness
• confusion
• loss of directional sense
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is advisable to keep it in a cool place between 15 to 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication for a longer period.

Appearance

White hard capsule containing white powder

Package unit

30 capsules/bottle, 100 capsules/bottle