Kirotin 5mg (Rosuvastatin Calcium)

Adult dosage

For primary hypercholesterolemia, mixed dyslipidemia, and dysbetalipoproteinemia, the initial dose is 5 milligrams taken once a day at any time irrespective of meals. If necessary, the maintenance dose can be increased up to 10 milligrams once a day, and adjustments can be made to a maximum of 20 milligrams based on LDL cholesterol levels and patient response, with intervals of at least 4 weeks.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is once daily 5 milligrams to 20 milligrams. The dosage should be adjusted according to the individual patient's treatment goals with an interval of 4 weeks or more.

This medication should not be used in patients with hypersensitivity to its components or those with active liver disease. Patients with muscle disorders or those taking cyclosporine, as well as patients with severe renal impairment, should not take this medication. Pregnant women, breastfeeding women, and women of childbearing potential should fully understand the risks of not being pregnant and the risks to the fetus before taking this medication. Patients at high risk for myopathy or rhabdomyolysis, for example, moderate renal impairment, hypothyroidism, or a family history of muscle disorders, should not take this medication at a 40mg dosage. Additionally, patients with genetic issues such as lactose intolerance should not take this medication. Patients who consume alcohol heavily or have a history of liver disease should undergo regular liver function tests before and during treatment with this medication. If symptoms of muscle pain or weakness occur, it is essential to inform the physician immediately, and blood tests may be necessary to determine the extent of muscle damage. In cases of severe muscle symptoms or abnormal blood test results, the use of this medication may need to be discontinued. This medication can cause side effects such as abnormal liver function, muscle pain, headache, digestive disturbances, so if symptoms persist or worsen, consult with healthcare professionals. There may be potential interactions when taken with other medications, so inform the healthcare provider of all medications being taken. Do not use this medication during pregnancy or breastfeeding, and if pregnancy is planned, proper contraception should be used. In case of overdose, there is no specific antidote, so seek medical attention immediately for appropriate treatment and monitor liver function and muscle levels. Dizziness may occur while taking this medication, so caution should be exercised when driving or operating machinery. Before taking this medication, always consult with a doctor or pharmacist to confirm the safe usage appropriate for your health condition.

Serious side effects

Hypersensitivity reactions including angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, severe muscle weakness, respiratory distress, ophthalmoplegia, jaundice, hepatitis, Stevens-Johnson syndrome, eosinophilia with systemic symptoms related drug reaction syndrome (DRESS), immune-mediated necrotizing myopathy, acute renal failure, oliguria, fatal and non-fatal liver failure, severe skin reactions, severe allergic reactions, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• hives
• muscle pain
• weakness

This medication should be stored in a tightly closed container to prevent air or moisture exposure. Additionally, it is best to store it at a temperature between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

PTP packaging - 30 tablets/PTP [(15 tablets / PTP x 2)]