Medication info
Krafloxin Tablets 500 mg (Levofloxacin Hydrate)

Krafloxin Tablets 500 mg (Levofloxacin Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›512.3mg / 1 tablet
Manufacturer / importer
한국휴텍스제약(주)
Appearance
Pink rectangular film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201701431 · Approved 2017.03.27 · Insurance code 649103410

Summary

Main use
Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia, etc.
Who takes it
Adults
Adult dose
In adults, levofloxacin is typically orally administered once daily at 250–750 mg. For patients with normal renal function (creatinine clearance greater than 80 mL/min), the dosing regimens and duration are as follows: - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia, etc.

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complex urinary tract infections
  • simple urinary tract infections
View approved original text

This drug is effective against various bacteria including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and is used to treat complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and mild to moderate urinary tract infections. However, this medication is a fluoroquinolone and has a risk of serious side effects, so it should be used cautiously only when there are no alternative treatments for these conditions. Therefore, this medication is an antibiotic effectively used for the treatment of serious infections.

How to take

Adult dose

In adults, levofloxacin is typically orally administered once daily at 250–750 mg. For patients with normal renal function (creatinine clearance greater than 80 mL/min), the dosing regimens and duration are as follows: - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute

Precautions

This drug is a fluoroquinolone antibiotic and can cause serious side effects such as tendonitis, tendon rupture, peripheral neuropathy, and central nervous system adverse reactions. Particularly, it should not be used in patients with myasthenia gravis, as it can worsen symptoms. This medication should be used only when there are no alternative treatments for specific acute bacterial infections. Caution should be exercised in elderly patients, patients with renal impairment, and those on corticosteroid therapy due to a higher risk of tendon rupture. If pain or inflammation occurs, treatment should be stopped immediately. There is also a risk of seizures, so it should be administered with caution to patients with epilepsy or those at risk of convulsions. This drug can cause various adverse reactions such as allergic reactions, severe skin reactions, liver and kidney dysfunction, blood disorders, and gastrointestinal disturbances, so symptoms should be monitored closely. Particularly, photosensitivity reactions can occur, so exposure to strong sunlight or artificial ultraviolet light should be avoided. Caution is also necessary as dizziness or drowsiness may occur when driving or operating machinery. This medication may interact with certain drugs, so be sure to inform healthcare professionals if taking other medications. It should not be used in pregnant or nursing women, adolescents under 18 years of age, or patients who have hypersensitivity to this drug or similar medications. In the event of overdose, central nervous system symptoms and cardiac abnormalities may occur, necessitating immediate treatment. Patients should consult a doctor immediately if any abnormal symptoms appear during treatment, as discontinuation may be necessary.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning headache, seizures, altered consciousness, vision disturbances, paralysis, changes in urination

Mild side effects

  • Insomnia
  • dizziness
  • headache
  • tremors
  • anxiety
  • agitation
  • confusion
  • nausea
  • vomiting
  • abdominal discomfort
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  • diarrhea
  • loss of appetite
  • abdominal pain
  • abdominal bloating
  • dyspepsia
  • stomatitis
  • glossitis
  • dry mouth
  • constipation
  • itching
  • taste disorder
  • constipation
  • fungal infection
  • drowsiness
  • excitement
  • thirst
  • allergic reactions
  • palpitations
  • increased serum creatinine
  • elevated liver enzymes
  • leukopenia
  • anemia
  • decreased hemoglobin
  • thrombocytopenia
  • anemia
  • blood sugar fluctuations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius (room temperature) to preserve the drug's efficacy over time.

Appearance and packaging

Appearance

Pink rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.