Princapsule 75 mg (Pregabalin)

Adult dose

This medication is administered orally, divided into two doses per day regardless of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Initial dosage of 150 mg per day, which may be increased to 300 mg per day after 3 to 7 days, and subsequently increased to a maximum of 600 mg per day at 7-day intervals if necessary. - Central Neuropathic Pain: Initial dosage of 150 mg per day, which may be increased to 300 mg per day after a week.

Child dose

Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12 to 17 years, and administration is not recommended.

This medication is used as an anticonvulsant, and there may be an increased risk of suicidal thoughts or behaviors; thus, mood and behavior changes should be closely monitored during treatment. Patients with hypersensitivity to this drug or specific genetic issues such as lactose intolerance should not take this medication. Diabetic patients may need to adjust their blood sugar medication dosage due to weight gain, and should stop taking this medication immediately if signs of angioedema occur. Elderly patients should exercise caution due to risks of dizziness or drowsiness leading to falls, and may experience vision changes such as blurred vision. Withdrawal symptoms such as insomnia, headache, and anxiety may occur if the medication is abruptly discontinued, so consultation with healthcare professionals is advised. Patients with a history of drug abuse should be cautious of the potential for misuse of this medication. Patients with heart disease or renal dysfunction should consult with healthcare professionals before administration, and dose adjustments may be necessary in cases of severe respiratory depression in those with respiratory disorders or the elderly. Pregnant women should not take this medication during the early stages of pregnancy as it may pose risks to the fetus, and women of childbearing age should use effective contraception. Caution should be taken while driving or operating machinery due to risks of dizziness and drowsiness. This drug can cause serious skin reactions such as rash and Stevens-Johnson syndrome, so if any unusual symptoms occur, it should be discontinued immediately, and healthcare professionals should be notified. When used with other central nervous system depressants or opioid analgesics, the risk of respiratory depression increases, necessitating careful monitoring. In case of overdose, symptoms may include drowsiness, confusion, and depression, and treatments like hemodialysis may be necessary. Dosage adjustments are needed for children and the elderly, and consulting healthcare professionals is mandatory before administration to children, pregnant women, or nursing mothers. Keep the medication out of reach of children and do not transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), angioedema, facial swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash accompanied by fever, blisters, skin peeling, oral/ocular mucosal pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, pulmonary edema, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, liver abnormalities.

Mild side effects

• Dizziness
• drowsiness
• dry mouth
• increased appetite
• decreased appetite
• hypoglycemia
• confusion
• spatial disorientation
• irritability
• depression

This medication should be stored in a tightly closed container to protect it from air and moisture, preferably at room temperature between 15 to 30 degrees Celsius.

Appearance

A hard capsule with an upper reddish-brown part and a lower white part containing a powder that is white to pale yellow.

Package unit

30 capsules/bottle, 100 capsules/bottle