Shubastatin Tablets 10 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 mg once daily, and if lower levels of LDL cholesterol reduction are needed, the maintenance dose can be adjusted. The maintenance dose is 10 mg once daily, and most patients will be managed on this dose. The maintenance dose should be adjusted appropriately every 4 weeks or more based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 mg.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years) is 5 mg to 20 mg once daily. The dosing will be adjusted according to the recommended treatment goals for individual patients.

This medication should not be administered to certain patients. For example, patients who are allergic to this drug, have liver dysfunction, have muscle disorders, or have severe renal impairment should not take this medication. The use of this medication is restricted for women who are pregnant or breastfeeding, and for women of childbearing potential who do not use adequate contraception, due to the potential risk to the fetus. Patients at high risk for muscle-related side effects, such as those with hypothyroidism, a history of hereditary muscle disorders, alcohol addiction, or those taking certain medications in combination, should use this medication with caution. This drug contains lactose, so it should not be given to patients with lactose intolerance. Patients who consume large amounts of alcohol or have a history of liver disease should undergo liver function tests before taking this medication and should also have regular liver enzyme tests during treatment. If symptoms related to muscle pain, muscle weakness, or muscle damage occur, patients should promptly inform their doctor and discontinue the use of this medication if necessary. This medication may raise blood glucose levels in some patients, so those at risk of diabetes should manage their blood glucose carefully. This medication may interact with other drugs, so patients should inform their doctor or pharmacist of any other medications they are taking. Special caution is needed when taken with certain antiviral medications, immunosuppressants, antibiotics, and lipid-lowering medications. Pregnant or breastfeeding women should not take this medication, and women who could become pregnant should use adequate contraception. In cases of overdose, there are no specific antidotes, so treatment should be symptomatic, and liver function and muscle enzyme tests should be conducted as needed. This medication does not appear to have a significant effect on driving or operating machinery, but caution is advised due to the possibility of dizziness. Finally, it is important for patients to consult healthcare professionals immediately if any adverse reactions or uncomfortable symptoms occur during treatment.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe skin reactions, acute renal failure, oliguria, myopathy, rhabdomyolysis, severe muscle weakness, oculomotor weakness, serious liver damage, hyperbilirubinemia, severe headache, seizures, confusion, visual disturbances, paralysis, heart

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius to ensure the drug's efficacy is preserved.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle