Uniloba Tablet 20mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 milligrams once daily, and if more reduction in LDL cholesterol is needed, the maintenance dose can be adjusted accordingly. The maintenance dose for most patients is 10 milligrams once daily. The maintenance dose should be adjusted regularly based on LDL cholesterol levels, treatment goals, and patient response every 4 weeks or more, with a maximum increase to 20 milligrams once daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years), the typical dosage range is 5 milligrams to 20 milligrams once daily. The dose must be adjusted individually based on the recommended treatment goals for each patient.

This medication should not be administered to certain patients. For example, patients who are allergic to this medication, those with severely impaired liver function, those with muscle diseases, and women who are pregnant or breastfeeding should not take this medication. Additionally, care is needed for patients with severely impaired kidney function or those taking certain medications simultaneously. In particular, patients at high risk for muscle-related side effects should carefully consider dose adjustments or the necessity of administration. This medication may affect liver function; thus, patients with a history of liver disease or those who consume excessive alcohol should undergo regular liver function tests before and during treatment. If symptoms such as myalgia or muscle weakness occur, they should immediately inform their physician, and the administration of this medication may be stopped if necessary. These symptoms can rarely progress to serious muscle damage. This medication contains lactose, so patients with lactose intolerance are advised not to take it. There may be interactions with other medications during treatment, so all medications being taken should be disclosed to healthcare providers, particularly when taken with certain antivirals, antibiotics, immunosuppressants, or fibrate class medications. Women who could become pregnant should use appropriate contraception to avoid pregnancy, and if pregnancy is confirmed, they should immediately discontinue the medication. In case of overdose, there is no specific antidote, and treatment should be symptomatic along with monitoring of liver function and muscle enzyme levels. Lastly, this medication may show higher blood concentrations in Asians, so dosage adjustments may be necessary.

Serious side effects

Allergic reactions including urticaria and angioedema, chest tightness, difficulty breathing, respiratory distress, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, fatal and non-fatal liver failure, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, myopathy (including myositis), rhabdomyolysis, acute renal failure, oliguria, edema, severe muscle weakness

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• cough

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius. This will help ensure the medication's effectiveness for a long time.

Appearance

Pink round film-coated tablet

Package unit

Domestic use - 30 tablets/box [10 tablets/PTP x 3], Domestic use - 30 tablets/bottle, Export use - 30 tablets/box [10 tablets/PTP x 3], Export use - 100 tablets/box [10 tablets/PTP x 10], Export use - 30 tablets/bottle