Myeongmun Nepopam Hydrochloride Injection

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer the intravenous injection slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. When added to an infusion solution such as an electrolyte or glucose solution, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the administration time. It is recommended to avoid mixing this medicine with other drugs for injection. The dose may be adjusted as appropriate according to age and symptoms.

This drug is used as an injection, and care must be taken when opening the glass container as glass fragments may mix with the medication. This drug should not be used in certain patients. For example, patients with epilepsy or myocardial infarction, those taking specific antidepressants such as MAO inhibitors, individuals with allergic reactions to the drug, children under 15 years old, those with a history of seizures or issues urinating due to urethral and prostate problems, and patients with glaucoma and high intraocular pressure should not take this medication. Additionally, elderly patients, women who are pregnant or breastfeeding, and those taking anticholinergic medications should take special care when using this drug. Taking this drug may cause symptoms such as loss of appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, rapid heartbeat, thirst, difficulty urinating, injection site pain, headache, blurred vision, fatigue, and nervousness. This drug helps to alleviate inflammation or pain but is not a treatment for the underlying cause, so it should be used considering the severity of the symptoms. If the inflammatory symptoms are due to an infection, using only this drug may delay the diagnosis of the infection, so it should be used cautiously in conjunction with antibiotics or antifungals. For elderly patients, the minimum effective dose should be used, and attention should be paid to the occurrence of side effects, while patients with liver or kidney dysfunction may be affected in drug metabolism and elimination. This medication may cause drowsiness or decreased concentration, so it is advisable not to use it during tasks requiring alertness, such as driving or operating machinery. Care should be taken when using this drug in combination with other anti-inflammatory analgesics or certain neurological medications as side effects may increase. The use of this drug is not recommended for pregnant or breastfeeding women. It is not used for children under 15 years of age as its safety and effectiveness have not been established. In case of overdose, immediate consultation with a physician or pharmacist is required, and close monitoring of cardiac and respiratory functions may be necessary. It is advisable to avoid mixing this drug with other medications for injection, and it should be stored in a sealed container in a cool, dry place out of reach of children. Additionally, it should be kept out of direct sunlight and not transferred to another container.

• Loss of appetite
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• excessive sweating
• dizziness
• tachycardia
• palpitations
• thirst

This drug should be stored in a sealed container to prevent exposure to air or moisture. The storage temperature should ideally be maintained between 1 degree and 30 degrees Celsius.

Appearance

Clear glass ampoule containing a colorless transparent liquid

Package unit

For domestic use: 1 ampoule (2 mL) × 50, 1 ampoule (5 mL) x 50 For export: 1 ampoule (2 mL) × 10