Ilyang Bio Fluconazole Tablets 150 mg

Adult dose

The route of administration should be determined according to the patient's clinical condition. Because absorption of oral formulations is rapid and nearly complete, the doses of oral formulations (tablets, capsules, dry syrup) and injectable formulations are the same. Vaginal candidiasis: Administer a single oral dose of 150 mg of fluconazole. Systemic candidiasis, including candidemia, disseminated candidiasis, and other invasive Candida infections (peritoneum, endocardium, lungs, urinary tract, etc.): The usual dose of this drug is 400 mg as a single dose on the first day, followed from the next day by 200 mg once daily; the dose may be increased to 400 mg once daily according to the patient's response. The duration of treatment is determined by clinical response and medical judgment. Cryptococcal meningitis and cryptococcosis at other sites: The usual dose of this drug is 400 mg as a single dose on the first day, followed from the next day by 200-400 mg once daily. The duration of treatment is determined by clinical and mycological response, but treatment should generally continue for at least 6 ~ 8 weeks. To prevent recurrence of cryptococcal meningitis in patients with AIDS, administer 200 mg of this drug once daily indefinitely after the patient has completed all initial therapy. Prevention of fungal infections in immunocompromised patients at risk due to neutropenia caused by cytotoxic chemotherapy, radiation therapy, or bone marrow transplantation: Administer 50-400 mg of this drug once daily, depending on the patient's level of risk for fungal infection. A dose of 400 mg once daily is recommended for patients at very high risk of systemic fungal infection, such as those with severe neutropenia or expected prolonged neutropenia, as in bone marrow transplantation. For these patients, administer 400 mg starting 5-6 days before the anticipated onset of neutropenia and continue 400 mg for 1 week after the neutrophil count has increased to 1,000 cells/mm3 or more. For onychomycosis, administer 150 mg once weekly. Continue treatment until the fingernails or toenails have regrown (until new, uninfected nails have grown). New fingernails usually take 3-6 months to grow, and toenails take about 6-12 months; growth rate may vary by individual and age. Even after successful treatment with long-term administration, fingernails or toenails may sometimes remain damaged. Dermatophyte infections of the skin, including athlete's foot (tinea pedis), tinea corporis, jock itch (tinea cruris), and cutaneous candidiasis: The usual dose of this drug is 50 mg once daily or 150 mg once weekly for 2-4 weeks. However, athlete's foot may require treatment for 6 weeks depending on the course of the condition. For tinea versicolor, administer 50 mg once daily for 2-4 weeks. Older adults: If renal function is normal, the usual adult dose is generally administered; in cases of renal impairment (creatinine clearance 50 mL/min or less), reduce the dose or extend the dosing interval. Patients with renal impairment: This drug is excreted primarily in the urine unchanged. No dose adjustment is required for a single dose; however, when multiple doses are required, administer the usual dose only on the first day and adjust the dose from the next day as follows. Creatinine clearance > 50 mL/min: 100 % of the usual dose Creatinine clearance ≤50 mL/min (not on dialysis): 50% of the usual dose Patients on hemodialysis: 100% of the usual dose after each hemodialysis session Patients receiving hemodialysis should receive 100% of the usual dose after each hemodialysis session. On days without dialysis, the dose should be reduced according to creatinine clearance.

This medication is an azole antifungal agent used for the treatment of fungal infections. This medication should not be used in certain patients. For example, patients who are allergic to this medication or other azole drugs, pregnant women or women who may become pregnant, and nursing mothers should not take this medication. Additionally, caution is necessary as it may pose risks when used with certain drugs, especially if taken with medications that affect the heart or prolong the QT interval, as serious side effects such as arrhythmias may occur. This medication contains lactose, and patients with lactose intolerance or related genetic disorders should avoid taking it. Patients with impaired kidney or liver function, heart disease, or electrolyte imbalances should use this medication with caution. This medication may affect liver and kidney function, so blood tests and liver and kidney function tests are recommended before and during treatment. Some patients may experience side effects such as headache, abdominal pain, diarrhea, elevated liver enzymes, skin rash, and rarely serious liver toxicity or blood abnormalities may occur. This medication has various interactions with other drugs, so patients taking other medications must consult a doctor or pharmacist. Pregnant women should avoid taking this medication as it may increase the risk of congenital malformations or miscarriage. If planning a pregnancy or currently pregnant, this medication should be avoided. Nursing mothers should also consider discontinuing breastfeeding or exploring alternative treatments since this medication is excreted in breast milk. It has not been sufficiently established for safety and efficacy in infants under 6 months of age and should only be used in special cases. Dizziness or seizures may occur with this medication, so caution is advised when driving or operating machinery. In case of overdose, hallucinations or abnormal behavior may occur, and immediate consultation with healthcare professionals for appropriate treatment is required.

Agranulocytosis, leukopenia, neutropenia, thrombocytopenia, anaphylaxis, angioedema, hypertriglyceridemia, hypercholesterolemia, hypokalemia, insomnia, drowsiness, headache, seizures, dizziness, sensory disturbances, taste disturbances, tremors, vertigo, Torsade de pointes, QT prolongation, abdominal pain, diarrhea, nausea, vomiting, dyspepsia, abdominal distension, dry mouth, increased ALT, increased AST, increased serum alkaline phosphatase, cholestasis, jaundice, increased bilirubin, hepatotoxicity, hepatic failure, hepatocyte necrosis, hepatitis, hepatocellular damage, rash, itching, urticaria, increased sweating, drug rash, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, exfoliative dermatitis, facial edema, hair loss, drug reactions with eosinophilia and systemic symptoms, myalgia, fatigue, lethargy, weakness, fever, adrenal insufficiency, hallucinations, psychotic behavior

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. This way, the medication's efficacy and safety can be preserved for a longer duration.

Appearance

Pink, oval-shaped tablet

Package unit

30 tablets/bottle