Crashed Tablet 500 mg (Clarithromycin)

Adult dose

Adults: The usual dose is 250 mg (of clarithromycin potency) twice daily. For severe infections, the dose is 500 mg (of clarithromycin potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250 mg (of clarithromycin potency) once daily, or, for severe infections, 250 mg (of clarithromycin potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: The dose is 500 mg (of this drug's potency) twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this drug at 500 mg (of its potency) 3 times daily in combination with omeprazole 40 mg once daily for 14 days, followed by omeprazole 40 mg once daily for 14 consecutive days. That is, administer clarithromycin at 500 mg (of its potency) 3 times daily for 14 days (days 1～14), and omeprazole 40 mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients allergic to the additives or active ingredients contained in this medication, patients with certain heart diseases, or patients with severely impaired liver or kidney function should not be administered. Furthermore, pregnant or breastfeeding women, as well as patients taking certain medications, may be at risk if they use this medication. Patients with weak liver or kidney function, elderly patients with heart disease, and patients taking other antibiotics should use this medication with caution. This medication can cause various side effects, although rare, such as serious allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney problems, skin rashes, and central nervous system symptoms, so if any abnormal symptoms occur, immediate consultation with a doctor is necessary. To prevent the development of antibiotic-resistant bacteria, it is important to confirm the susceptibility to the causative bacteria and to take it only for the necessary duration. This medication may interact with other drugs, particularly those affecting the heart or drugs metabolized by the liver, so it is essential to consult a doctor or pharmacist before use. Pregnant or breastfeeding women are advised not to use this medication, and if it must be used, breastfeeding should be stopped. In children, safety and effectiveness have not been sufficiently studied, so there may be restrictions on use depending on age. Elderly patients may require dose adjustments due to increased blood drug concentrations from decreased kidney function. During the use of this medication, regular tests such as liver and kidney function tests are necessary, and if there are any abnormal findings, treatment should be stopped immediately and follow the doctor's instructions. In the case of overdose, gastrointestinal disturbances or central nervous system symptoms may occur, so if symptoms appear, immediate hospital visit for appropriate treatment is required. This medication may have reduced absorption when taken with certain preparations, so caution is needed during administration.

Shock, anaphylactic symptoms, dyspnea, convulsions, redness, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, appetite loss, constipation, stool discoloration, membrane colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltrate, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis acute exacerbation, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucination, psychosis, depersonalization, convulsions, tremors, paresthesia, behavior changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, increased CPK, elevated serum and urine myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, paraesthesia, arthralgia, myalgia, olfactory disorder, tinnitus, auditory impairment, hypoglycemia, purpuric rash, acute generalized eruptive pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, venous thrombophlebitis at injection site, injection site pain, inflammation at injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, premature beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is important to store it in a cool, dry place away from direct light. The storage temperature should be maintained between 15 to 30 degrees Celsius.

Appearance

Yellow oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle