Nustatin AL Tablet 20 mg (Rosuvastatin Calcium)

Adult dose

Take once daily at any time regardless of meals. The initial dose is 5 mg once daily and can be adjusted to a maintenance dose as needed. Most patients maintain at 10 mg once daily, and adjustments should be made based on LDL-cholesterol levels and patient response at intervals of more than 4 weeks. The maximum dose can be increased to 20 mg once daily.

Child dose

Pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia should be dosed at 5 mg to 20 mg once daily. The dose should be adjusted according to the individual treatment goals over a period of more than 4 weeks.

This medication should not be used in certain patients. For example, patients who are allergic to any ingredients of this medication, have liver dysfunction, have muscle diseases, severely impaired kidney function, or are pregnant or breastfeeding should not take this medication. Additionally, the high-dose use of this medication is contraindicated in patients at risk for myopathy or rhabdomyolysis. Risk factors include moderate to severe kidney impairment, hypothyroidism, a family history of genetic muscular disorders, and alcoholism. This medication contains lactose, so patients with lactose intolerance should also avoid using it. Before administration, liver function tests and muscle-related tests should be conducted, and regular monitoring should continue during treatment. If symptoms such as muscle pain, weakness, fatigue, or fever occur, notify healthcare personnel immediately. This medication may interact with other drugs, so inform healthcare personnel of any other medications currently being taken, especially in combination with fibrates, cyclosporine, and certain antiviral agents. Women of childbearing potential should use appropriate contraceptive methods and avoid taking this medication while pregnant or breastfeeding. In case of overdose, there is no specific antidote, and treatment should be managed based on symptoms along with liver and muscle function tests. Caution is advised due to the possibility of dizziness when driving or operating machinery. Finally, if severe rash or allergic reactions occur while taking this medication, discontinue immediately and consult healthcare personnel.

Serious side effects

Hypersensitivity reactions including hives and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), severe myopathy, ocular myopathy, rhabdomyolysis, liver failure, jaundice, acute renal failure, oliguria, difficulty breathing, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe swelling, elevated blood pressure, severe allergic reactions, severe bleeding

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• cough

This medication should be stored in a closed container to prevent air and moisture from entering. It should be stored at room temperature, between 1 and 30 degrees Celsius, and not in excessively hot or cold conditions.

Appearance

Pink round film-coated tablet

Package unit

Domestic use - 30 tablets/box [10 tablets/PTP*3], Domestic use - 100 tablets/bottle, Export use - 28 tablets/box [14 tablets/PTP*2]