Cimetidine Tablet 200 mg (Cimetidine)

Adult dose

As cimetidine, administrate 400 mg orally twice a day (in the morning and at bedtime) or 800 mg once a day at bedtime. Additionally, administer 300 mg orally four times a day (after meals and at bedtime), and it can be increased up to 1.6 g total with doses of 400 mg orally four times a day (after meals and at bedtime). For acute gastritis and acute exacerbation of chronic gastritis, administer 200 mg twice a day or 400 mg once a day.

Child dose

Administered orally divided at a dose of 20–40 mg per kg of body weight per day.

When this drug is used in injection form, care must be taken when cutting the glass container. If glass fragments are mixed in, abnormal reactions may occur, so special caution is needed for children and the elderly. This drug should not be used in patients with an allergy to this medication or its components, those at risk of specific arrhythmias, and patients with genetic lactose intolerance. Patients with impaired kidney or liver function, those with a history of drug allergies, elderly patients, children, and those undergoing dialysis should be administered this drug with caution, and patients with symptoms of gastric cancer should use it only after confirming malignancy. Rare side effects may include decreased blood cell counts, liver function abnormalities, kidney dysfunction, allergic reactions, endocrine issues, gastrointestinal problems, neurological disturbances, irregular heart rhythms, and severe skin reactions; if any unusual symptoms occur, consult a doctor immediately. Use the minimum effective dose while monitoring treatment effectiveness and undergo regular blood tests and liver and kidney function tests. Elderly patients or those with chronic illnesses may have an increased risk of pneumonia, so caution is necessary. When taking this drug with other medications, consultation with a doctor or pharmacist is required to adjust dosages due to potential interactions, especially with anticoagulants, anticonvulsants, antidepressants, and antibiotics. Pregnant or nursing women should only use this medication if absolutely necessary, as its safety has not been established; it is recommended to stop breastfeeding during treatment. Safety has not been sufficiently confirmed for children, so it should be administered cautiously, and elderly patients may need to reduce the dose or prolong dosing intervals due to decreased kidney function. In the case of overdose, serious side effects such as respiratory depression may occur, and immediate medical attention is required. When administered as an injection, avoid rapid infusion to prevent arrhythmias or hypotension.

Serious side effects

General malaise, weakness, subcutaneous bleeding, mucosal bleeding, fever (early symptoms of hematological abnormalities), jaundice, shock, anaphylactic-like reactions (generalized urticaria, difficulty breathing), seizures, loss of consciousness, confusional states (anxiety, psychosis, depression, excitement, hallucinations, disorientation), skin mucosa syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), epidermal necrosis, erythema multiforme, exfoliative dermatitis, generalized exfoliative erythema, hypotension, respiratory depression

Mild side effects

• Leukopenia
• granuloctyopenia
• agranulocytosis
• thrombocytopenia
• pancytopenia
• aplastic anemia
• hepatitis
• elevated AST
• ALT
• interstitial seizures

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is best to store it at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness for a longer time.

Appearance

Light green round tablet

Package unit

1000 tablets/bottle