Glodilol Tablet (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor’s instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medicine per dose twice daily, then take 25 mg per dose twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg per dose twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the standard treatment regimen already being administered (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) Initial treatment is generally 3.125 mg of this medicine per dose twice daily for 2 weeks. If the patient tolerates this treatment well, increase to 6.25 mg per dose twice daily for 2 weeks, then increase to 12.5 mg per dose twice daily for 2 weeks, and then increase to 25 mg per dose twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually up to the dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less and 50 mg per dose twice daily for patients weighing over 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with food slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used in certain patients. For instance, it should not be administered to patients who are allergic to this drug or any of its components, those experiencing cardiogenic shock, patients with excessively slow heart rates, those with cor pulmonale, and patients with diabetic ketoacidosis, among others. Additionally, caution is warranted for patients with respiratory diseases such as asthma or chronic obstructive pulmonary disease since this medication may constrict bronchial muscles and worsen symptoms. It is advised that pregnant or breastfeeding women refrain from taking this medication. Particular care should be taken when administering this drug to diabetic patients, those with a history of severe allergic reactions, patients with hypotension, and those with impaired kidney or liver function. While on treatment, patients may experience symptoms such as dizziness, headache, and fatigue. In serious cases, severe side effects such as bradycardia, blood pressure drop, or worsening heart failure may occur, so regular medical check-ups are necessary. Sudden discontinuation of this medication may exacerbate heart-related symptoms, thus it should be reduced gradually according to a doctor's instructions. Additionally, there may be interactions when taken with other medications, so it is essential to inform the doctor or pharmacist of any other medications being taken. In case of overdose, symptoms like heart dysfunction, breathing difficulties, or altered consciousness may arise, requiring immediate contact with a medical institution for appropriate treatment. When storing this medication, it should be kept in a light-protected container and out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light, so it should be stored in a container that blocks light. It is also recommended to keep it at room temperature between 1 to 30 degrees Celsius.

Appearance

White round tablet

Package unit

For domestic use - 100 tablets/box [10T/PTP*10], For domestic use - 90 tablets/box [10T/PTP*9]