Tagma Tablet 200 mg (Cimetidine)

Adult dosage

For cimetidine, an oral dose of 400 mg twice daily (morning and bedtime) or a single dose of 800 mg once daily (at bedtime). Alternatively, take 300 mg four times daily (after meals and at bedtime). The dose can be increased up to 400 mg four times daily (after meals and at bedtime) for a total of 1.6 g. For the acute exacerbation of acute gastritis and chronic gastritis, administer 200 mg twice daily or 400 mg once daily.

Children's dosage

Administer 20-40 mg per kg of body weight divided orally per day.

When using this medication with glass ampule injections, care must be taken when cutting the container as glass fragments may mix in. Special caution is required when used in children and the elderly. Patients who are allergic to or have had hypersensitivity reactions to any of the components of this medication should not use it. Additionally, patients taking dofetilide, which may increase the risk of certain cardiac arrhythmias, should not take this medication. Patients with renal or liver function issues may have increased concentrations of this medication in their bodies, so dosage needs to be adjusted or the administration interval increased. Patients undergoing dialysis should take this medication after dialysis, and caution should be exercised in children under 19 years of age and elderly patients. This medication may mask symptoms of gastric cancer, so it should only be used after confirming the malignancy. Patients infected with Helicobacter pylori should undergo treatment to eradicate the bacteria. Patients allergic to Yellow No. 4 dye present in this medication should also use it cautiously. This medication can decrease blood cell counts, so if symptoms such as generalized malaise, bleeding, and fever appear, testing should be done, and administration should be stopped immediately. Liver or renal function abnormalities may occur, so if symptoms of jaundice, hepatitis, or renal failure arise, administration should be stopped immediately and treated. Rarely, severe allergic reactions, skin disorders, or neurological symptoms may occur; if such symptoms arise, the medication must be stopped immediately. This medication may also cause endocrine side effects such as gynecomastia, increased milk secretion, and erectile dysfunction. Gastrointestinal symptoms such as abdominal distension, constipation, and diarrhea may occur. Symptoms of neuropsychiatric disorders or cardiovascular anomalies have been reported rarely, so elderly patients or those with renal failure should exercise extra caution. This medication may interact with other medications, changing blood concentrations, so it is crucial to consult with a doctor about any concurrent medications. During pregnancy, the safety is uncertain, so it should be used cautiously only when necessary, and during breastfeeding, it is best to discontinue nursing. Experience with this medication in children is limited, so it should only be administered in special cases. Elderly patients, with renal function declining, should use it cautiously by reducing dosage and increasing administration intervals. Overdoses may lead to respiratory suppression, requiring immediate medical attention. When administered intravenously, it should be injected slowly to reduce side effects. Store in a secure location out of reach of children and do not transfer to another container.

Serious side effects

Generalized malaise, weakness, subcutaneous bleeding, mucosal bleeding, fever (initial symptoms of leukopenia, agranulocytosis, aplastic anemia, thrombocytopenia, pancytopenia), immune hemolytic anemia, jaundice, hepatitis, elevation of AST and ALT, perivenous hepatic fibrosis, interstitial nephritis, acute renal failure, interstitial nephritis, urinary retention, elevated BUN, fever, renal dysfunction, shock, anaphylactoid reactions, hypersensitivity vasculitis, rash

Mild side effects

• Fatigue
• fever
• generalized heat sensation
• dysuria
• myalgia
• arthralgia
• pancreatitis
• alopecia
• gynecomastia
• galactorrhea

This medication should be stored in a sealed container that blocks light, preferably at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevent degradation.

Appearance

Light green round tablet

Package unit

1000 tablets/bottle