Medication info
Nefirin Capsule 150 mg (Pregabalin)

Nefirin Capsule 150 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
알보젠코리아(주)
Appearance
A hard capsule with a white upper part and a white lower part containing a white powder that is white or pale yellow.
Packaging
30 capsules/bottle, 200 capsules/bottle
Approval status
Active

MFDS item code 201109223 · Approved 2011.10.27 · Insurance code 652603060

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication, Pregabalin, is administered orally in divided doses of the total daily dose twice a day, regardless of food intake. 1. Neuropathic pain 1) Peripheral neuropathic pain - Starting dose: 150 mg per day - May increase to 300 mg per day after 3 to 7 days. - Further may be increased up to a maximum of 600 mg per day at 7-day intervals if necessary. 2) Central neuropathic pain - Starting dose: 150 mg per day
Child dose
Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12-17 years, hence administration is not recommended.

Ingredients

Manufacturer
알보젠코리아(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • epilepsy
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to relieve peripheral and central neuropathic pain in adults. It is also utilized as an adjunct treatment for partial seizures, with or without secondary generalization, in patients with epilepsy. Additionally, it is effective in relieving pain caused by fibromyalgia. In summary, this drug is used for neuropathic pain, adjunctive treatment of partial seizures in epilepsy, and treatment of fibromyalgia.

How to take

Adult dose

This medication, Pregabalin, is administered orally in divided doses of the total daily dose twice a day, regardless of food intake. 1. Neuropathic pain 1) Peripheral neuropathic pain - Starting dose: 150 mg per day - May increase to 300 mg per day after 3 to 7 days. - Further may be increased up to a maximum of 600 mg per day at 7-day intervals if necessary. 2) Central neuropathic pain - Starting dose: 150 mg per day

Child dose

Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12-17 years, hence administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so if you experience any mood or behavioral changes while taking it, you should consult a doctor immediately. It should not be administered to patients with hypersensitivity to this drug or specific hereditary diseases such as lactose intolerance. Diabetic patients may need to adjust their blood sugar control medications due to weight gain, so caution is advised. If symptoms of angioedema, such as swelling around the face or mouth, occur, the medication should be discontinued immediately. Elderly patients are at risk of falls due to dizziness or drowsiness, so they should be particularly cautious when starting the medication. Temporary blurred vision or changes in vision may occur, but symptoms may improve after discontinuation of the drug. Discontinuing this medication suddenly may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered off according to a doctor's instructions. There is a risk of drug abuse, so patients with a history of drug abuse should be more cautious. Patients with decreased kidney function may require dosage adjustment. Patients with heart disease should be vigilant for symptoms of heart failure while taking this medication. Taking this medication with other drugs that have central nervous system depressant effects may increase the risk of drowsiness or respiratory depression. In early pregnancy, there may be a risk of fetal malformations, so use during pregnancy must be approached with caution, and effective contraception is advised for women of childbearing age. During breastfeeding, because this medication may be transmitted through breast milk, a discussion with a doctor is necessary regarding whether to discontinue breastfeeding or the medication. This medicine can cause dizziness and drowsiness, so driving or operating dangerous machinery should be avoided until symptoms are confirmed. If severe skin rashes or allergic reactions occur, discontinue use immediately and notify healthcare personnel. In case of overdose, confusion, drowsiness, seizures, etc., may occur, and appropriate treatment should be sought in a hospital if necessary. Keep out of reach of children and do not transfer to another container for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever and respiratory abnormalities, yellowing of skin or eyes, profound lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, significantly reduced urine production

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • spatial disorientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • sexual hypersensitivity
  • restlessness
  • anxiety
  • mood fluctuation
  • emotional blunting
  • emotional elevation
  • difficulty in finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • indifference
  • ataxia
  • motor coordination abnormality
  • balance disorder
  • amnesia
  • attention disorder
  • memory disorder
  • tremor
  • dysarthria
  • sensory abnormality
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. Additionally, it is important to store it at room temperature between 15 and 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

A hard capsule with a white upper part and a white lower part containing a white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 200 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.