Medication info
Donggu Levofloxacin Hydrate Tablets 500mg

Donggu Levofloxacin Hydrate Tablets 500mg

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›512.3mg / 1 tablet
Manufacturer / importer
(주)동구바이오제약
Appearance
Pink rectangular film-coated tablet
Packaging
28 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200800333 · Notified 2008.01.08 · Insurance code 657304180

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia
Who takes it
Adults
Adult dose
Ordinary adults should take 250 to 750 mg of levofloxacin orally once daily. For patients with normal kidney function (creatinine clearance greater than 80 mL/min): - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10 to 14 days - Chronic

Ingredients

Manufacturer
(주)동구바이오제약

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbations of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complex urinary tract infections
  • uncomplicated urinary tract infections
View approved original text

This drug is an antibiotic effective against various strains, used for bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, etc. It is mainly used for complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, and is also helpful in treating acute sinusitis, chronic bacterial prostatitis, complex urinary tract infections, and uncomplicated urinary tract infections. However, this drug is a fluoroquinolone and carries a significant risk of serious adverse reactions; it should only be used when other treatment options are unavailable. Therefore, it must be used cautiously only when necessary and is effective in improving major infectious diseases.

How to take

Adult dose

Ordinary adults should take 250 to 750 mg of levofloxacin orally once daily. For patients with normal kidney function (creatinine clearance greater than 80 mL/min): - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10 to 14 days - Chronic

Precautions

This drug can cause serious side effects such as tendonitis and tendon rupture, peripheral neuropathy, central nervous system disorders, and exacerbation of myasthenia gravis. If such symptoms occur, the medication should be discontinued immediately, and it should not be used in patients with myasthenia gravis. Particular attention is needed for the elderly, patients with impaired kidney function, and those taking corticosteroids, as they have an increased risk of tendon rupture. If pain or inflammatory symptoms occur, the medication should be stopped and rest taken. This drug is contraindicated for certain patients, such as those with hypersensitivity to this drug or similar medications, those with a history of tendonitis or tendon rupture, children and adolescents in a growth period, pregnant or breastfeeding women, and patients with epilepsy. Patients with severely impaired kidney function, central nervous system disorders, a history of seizures, the elderly, and diabetics should use this medication cautiously and closely monitor blood sugar and neurological symptoms. This drug can cause various side effects, including serious allergic reactions, psychiatric disturbances (anxiety, depression, hallucinations, etc.), cardiac arrhythmias, liver and kidney dysfunction, blood disorders, gastrointestinal disturbances, musculoskeletal issues, and severe skin reactions, pneumonia, etc., and anyone experiencing unusual symptoms should consult a physician immediately. This drug may interact with other medications, so caution is advised, especially when taken with non-steroidal anti-inflammatory drugs, antacids, iron supplements, calcium preparations, hypoglycemic agents, and anticoagulants, and dosing intervals may need to be adjusted or blood tests conducted to monitor the condition. Pregnant or breastfeeding women should not take this medication, nor should it be given to children or adolescents in a growth period. Elderly patients should adjust the dose and administration interval due to prolonged retention of the drug in the body resulting from impaired kidney function, and medication should be discontinued immediately if liver dysfunction occurs. In the case of overdose, central nervous system symptoms and cardiac issues may arise, necessitating immediate treatment and monitoring, and this drug is not removed by dialysis. Finally, this drug has been reported to cause side effects such as joint abnormalities in animal tests, so caution is necessary regarding joint-related symptoms.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, breathlessness or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

  • Nausea
  • diarrhea
  • vaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • dyspepsia
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  • stomatitis
  • glossitis
  • thirst
  • constipation
  • genital candidiasis
  • candidiasis
  • taste disturbance
  • vomiting
  • fungal infection
  • genital itching
  • headache
  • neurosis
  • erythematous rash
  • decreased appetite
  • drowsiness
  • agitation
  • dry mouth
  • tremors
  • allergic reactions

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to prevent exposure to air or moisture, and at a temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness.

Appearance and packaging

Appearance

Pink rectangular film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.