Palodel tablets (bromocriptine mesylate)

Key information summary

Efficacy & effects

This medication is used to prevent and suppress milk secretion, treat male and female hypogonadism and galactorrhea caused by hyperprolactinemia. It also helps alleviate symptoms such as breast symptoms due to infertility and menstrual irregularities, premenstrual headaches, mood changes, and edema. For patients with acromegaly, it is used in conjunction with surgery or radiation therapy to lower blood growth hormone levels. It is also effective in improving symptoms in patients with Parkinson's disease. This versatility helps improve the patient's condition.

Dosage

Take the medication always immediately after meals. It is preferable to use a titration regimen to minimize adverse reactions and maximize effectiveness for most indications. On the first day, administer 1.25 mg at bedtime, and for the next 2-3 days, administer 1.25 mg in the morning and evening; thereafter, increase the dose by 1.25 mg at intervals of 2-3 days to a maintenance dose of 2.5 mg twice a day.

Precautions

This medication should not be administered to certain patients. For example, patients already taking ergot alkaloids or those who have had allergic reactions to this medication or ergot alkaloids, patients with severe cardiovascular disease, arterial occlusion, or Raynaud's disease, patients with uncontrolled hypertension, patients with severe psychiatric disorders, patients with very poor liver function, and nicotine abusers should not use this medication. Also, patients with severely progressive pituitary tumors, women who are pregnant or may become pregnant, patients with liver or kidney issues, patients with peptic ulcers, patients with a history of psychiatric disorders, patients with a history of myocardial infarction, and children and the elderly should use this medication with caution. While taking this medication, blood pressure may drop suddenly, and dizziness, drowsiness, or sudden sleep onset may occur, so it is advised to avoid driving or operating dangerous machinery. Initially, symptoms such as nausea or vomiting may also occur, so caution is warranted. Since this medication is metabolized and excreted by the liver and kidneys, patients with liver impairment or kidney impairment require dosage adjustment and monitoring. Additionally, this medication may interact with several drugs, so it is essential to inform your healthcare provider if you are taking other medications. Women planning to become pregnant or who are pregnant should consult with a doctor before taking this medication, and should be monitored carefully during pregnancy. It is advised that breastfeeding women do not take this medication. Children and the elderly should also use this medication with caution, and dosage should be adjusted or taken according to a physician's instructions. In the case of overdose, symptoms such as vomiting, dizziness, hypotension, and drowsiness may occur, and immediate medical attention should be sought.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, lightning-like headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urinary

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