
Key information summary
Efficacy & effects
This medication is used to alleviate menopausal symptoms following natural menopause or oophorectomy and symptoms due to deterioration of the function of the urogenital organs.
Dosage
As Estradiol Valerate, administer 10 mg intramuscularly every 2 to 4 weeks. The treatment duration depends on the indication and patient condition.
Precautions
This drug is a hormone agent used in postmenopausal women; it may increase the risk of endometrial cancer, so if the patient has not undergone hysterectomy, progesterone must be taken as directed by a physician. It should not be used for the purpose of preventing cardiovascular diseases, and caution is needed as there may be an increased risk of dementia, especially in women over 65 years old. It should not be administered to patients with unexplained genital bleeding, suspected estrogen-dependent cancers, patients with a history of thrombosis, or currently with thrombosis. Women with impaired liver function, pregnant women, or breastfeeding women should not use this medication. Patients with specific conditions or risk factors such as uterine fibroids, hypertension, diabetes, liver disease, migraines, and asthma should use this medication cautiously, and if any unusual symptoms occur during treatment, they should consult a physician immediately. Long-term use of this medication may cause side effects such as breast pain, edema, thrombosis, and regular examinations are required. Additionally, this medication may interact with other drugs, so if the patient is taking other medications, they must inform their physician or pharmacist. Pregnant women, women who may become pregnant, and breastfeeding women should not take this medication, and special caution is required for the elderly.
Side effects
Thrombosis, rash and other hypersensitivity reactions, vascular thrombosis, pulmonary embolism, thrombophilia, increased blood pressure, angioedema, jaundice, migraine-type headache, increased risk of dementia
