Progynova 28 Tablets 1 mg (Estradiol Valerate)

Key information summary

Efficacy & effects

This medication is used as hormone replacement therapy to alleviate the menopausal symptoms in postmenopausal women. It also helps to prevent osteoporosis in women at high risk of fractures. Women with a uterus should take progestogen for 12 days each month to ensure safe and effective treatment. This medication is used to relieve uncomfortable menopausal symptoms and maintain bone health.

Dosage

Administer 1 mg or 2 mg of estradiol valerate orally after meals. Continue therapy and take the next new package immediately without interruption. Adjust the dosage appropriately based on treatment progress. Swallow the tablet whole with a suitable beverage, and preferably take it at the same time every day.

Precautions

This medication may increase the risk of endometrial cancer in postmenopausal women; therefore, women with a uterus should receive additional hormone therapy according to their healthcare provider's guidance. The risk of vascular-related diseases such as thrombosis may increase while taking this medication, so patients with risk factors for thrombosis should consult their doctor thoroughly and be monitored carefully. If sudden vision changes, severe headache, jaundice, abnormal liver function, or a sudden spike in blood pressure occur, stop taking the medication immediately and inform your doctor. This medication should not be administered to patients with specific conditions or a history of certain diseases, particularly those with endometrial cancer, cerebrovascular disease, thromboembolism, liver disease, or pregnant women. Before administration, the patient's medical history and family history should be thoroughly reviewed, and regular physical examinations and gynecological check-ups should be performed; long-term use may increase the risk of cancer such as breast cancer, ovarian cancer, and endometrial cancer, thus regular testing is necessary. This medication may interact with other drugs, so be sure to inform your doctor or pharmacist of any other medications you are taking. Pregnant or breastfeeding women should not take this medication, and if pregnancy is confirmed during use, it must be stopped immediately. This medication is not used for children or adolescents as it may cause side effects such as premature closure of growth plates. In case of overdose, symptoms such as breast tenderness, abdominal distension, anxiety, and nausea may occur, but decreasing the dose will alleviate the symptoms, and no specific treatment is required. This medication should be stored out of reach of children and kept in its original container to prevent quality degradation or misuse.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, cough with abnormal breathing and fever, yellowing of skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Alternatives / Same-ingredient medications

• Estradiol depot injection 10mg (estradiol valerate)

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• 

  Progynova 28 Tablets 2 mg (Estradiol Valerate)

  Same ingredient

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