Progynova 28 Tablets 2 mg (Estradiol Valerate)

Adult dose

As estradiol valerate, take 1 mg or 2 mg orally after meals once daily. Continue treatment and immediately take the next new package without interruption. Adjust dosage appropriately according to the treatment progress. Swallow the tablet whole with adequate liquid, and ideally take it at the same time each day.

Child dose

This medication is not for use in children and adolescents.

This medication may increase the risk of endometrial cancer in postmenopausal women; therefore, women with a uterus must take additional progestogen as directed by their physician. It can also increase the risk of thromboembolic diseases such as thrombosis, so individuals with risk factors for thrombosis should consult their doctor thoroughly before use, and treatment should be discontinued immediately if any abnormal symptoms arise. If severe headaches or migraines worsen, or if there are sudden visual disturbances indicating signs of vascular obstruction, treatment should be stopped immediately. This medication should not be taken in cases of liver dysfunction, jaundice, hypertension, or during pregnancy, and if any of these symptoms occur, treatment should be stopped immediately. It should not be administered to patients with estrogen-dependent tumors, cardiovascular diseases, or a history of thromboembolic disease. Patients with severe liver, kidney, or heart diseases, or those with specific genetic disorders, should also avoid this medication. Pregnant or nursing mothers should not take this medication, and women who may become pregnant should confirm this before use. Regular physical examinations and gynecological check-ups should be conducted during the use of this medication, as the risks of breast cancer or endometrial cancer must be monitored. Additionally, this medication may interact with other drugs, so if any medications are being taken, it is essential to inform the doctor or pharmacist. In case of overdose, symptoms such as breast tenderness, anxiety, and nausea may occur, and dose reduction or symptomatic treatment may be required. Keep out of reach of children, and store it in its original container to prevent misuse or deterioration of the medication.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormality accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme drowsiness, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

Weight gain or loss, depressed mood, anxiety, decreased or increased libido, headache, dizziness, migraine, contact lens intolerance, palpitations, abdominal pain, nausea, indigestion, bloating, vomiting, rash, itching, nodular erythema, hirsutism, acne, muscle cramps, uterine/vaginal bleeding including spot bleeding, breast pain, breast tenderness, menstrual pain, vaginal discharge, premenstrual syndrome, breast size increase, edema, fatigue,

This medication should be stored in a tightly closed container to protect it from air or moisture, and it is best to keep it at a temperature between 1 and 30 degrees Celsius. This will maintain the effectiveness and ensure safe usage of the medication.

Appearance

Round, white, biconvex film-coated tablet

Package unit

28 tablets/PTP