Medication info

Serevent 50 Evohaler

Prescription medicationSuspensionApproval withdrawn
Ingredient · strength
Salmeterol Xinafoate Micronized›48.333mg / 100gFluticasone Propionate Micronized›66.667mg / 100g
Manufacturer / importer
(주)글락소스미스클라인
Appearance
A metered-dose aerosol containing a white to off-white suspension with a dose control valve.
Packaging
120 doses/can
Approval status
Approval withdrawn

MFDS item code 200108715 · Notified 2001.02.27

This product's status changed to Approval withdrawn on 2024.10.29. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Asthma treatment through bronchodilation and anti-inflammatory effects.
Who uses it
Adults · Children
Adult dosage
Adults and children over 12 years: The following doses should be sprayed according to the severity of the disease. Salmeterol 25 μg + Fluticasone Propionate 50 μg, 2 sprays twice a day or Salmeterol 25 μg + Fluticasone Propionate 125 μg, 2 sprays twice a day or Salmeterol 25 μg + Fluticasone Propionate 250 μg, 2 sprays twice a day.
Children's dosage
There is insufficient useful information regarding the use of this medication in children under 12 years.

Ingredients

Importer
(주)글락소스미스클라인

Efficacy & effects

Asthma treatment through bronchodilation and anti-inflammatory effects.

  • Asthma
View approved original text

Bronchodilators and inhaled corticosteroids are used together to effectively control asthma symptoms. Bronchodilators relax airway muscles, making breathing easier, while corticosteroids reduce inflammation, alleviating chronic airway inflammation. By using these two medications in combination, the frequency and severity of asthma attacks can be reduced, and breathing function in daily life can be improved. Therefore, for asthma patients, the combined administration of bronchodilators and inhaled corticosteroids is an appropriate treatment for symptom relief and disease management.

Dosage and Administration

Adult dosage

Adults and children over 12 years: The following doses should be sprayed according to the severity of the disease. Salmeterol 25 μg + Fluticasone Propionate 50 μg, 2 sprays twice a day or Salmeterol 25 μg + Fluticasone Propionate 125 μg, 2 sprays twice a day or Salmeterol 25 μg + Fluticasone Propionate 250 μg, 2 sprays twice a day.

Children's dosage

There is insufficient useful information regarding the use of this medication in children under 12 years.

Precautions

This medication expands the bronchi and makes breathing easier. However, it should not be used for acute asthma attacks or very severe asthma exacerbations. When acute symptoms occur, an immediate-acting alternative medication must be used, and this medication is for maintenance therapy of asthma or chronic obstructive pulmonary disease. Do not administer to those with allergies to this drug or its components, untreated respiratory infections, severe bronchiectasis, or severe asthma. Additionally, special caution should be exercised when using this drug in patients with heart disease, diabetes, hyperthyroidism, seizure disorders, pulmonary tuberculosis, hypokalemia, or chronic obstructive pulmonary disease. Various side effects such as breathing difficulty, wheezing, palpitations, muscle pain, rash, oral candidiasis may occur, and if symptoms appear, immediate consultation with a physician is necessary. This medication can interact with other medications, particularly when taken with heart medications, beta-blockers, antifungal agents, and certain antibiotics, so caution is required. It should only be used during pregnancy or breastfeeding when necessary, under the careful judgment of a physician, and its use is not recommended for children under 12 years as safety and efficacy have not been established in this age group. Elderly patients should use this medication with caution regarding cardiovascular reactions, and an overdose may result in serious symptoms such as heart issues, blood pressure changes, muscle spasms, or seizures, requiring immediate medical attention. This medication is administered via an inhaler, and it is important to learn the correct usage and regularly check the condition of the inhaler. After use, it is crucial to rinse the mouth with water to prevent oral candidiasis. Store in a cool, dry place out of reach of children, avoiding direct sunlight and high temperatures. Do not puncture or burn the can even if empty.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria, edema, angioedema → severe allergic reaction
  • Severe rash with fever, blistering, skin peeling, mucosal pain in mouth/eyes → severe skin abnormal reactions
  • Shortness of breath or difficulty breathing, asthma attacks, coughing with fever → respiratory issues
  • Skin or eyes turning yellow (jaundice), extreme lethargy → liver issues (jaundice)
  • Severe headaches, lightning pain, seizures, confusion, visual disturbances,

Mild side effects

  • Nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • awareness of heartbeat
  • headache
  • tremors
  • palpitations
  • tachycardia
  • atrial fibrillation
Show 23 more
  • nonspecific chest pain
  • bronchitis
  • rhinitis
  • laryngitis
  • oropharyngeal irritation
  • abdominal cramps
  • myalgia/myositis
  • muscle aches
  • joint pain
  • muscle cramps
  • menstrual irregularities
  • flushing
  • rash
  • urticaria
  • edema
  • angioedema
  • irritability
  • toothache
  • hyperglycemia
  • hoarseness/voice changes
  • oral and throat candidiasis
  • skin sensitivity reactions
  • anxiety

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can degrade due to air or light, so it should be stored in a tightly sealed container. Also, it is best to avoid direct sunlight and store it at room temperature.

Appearance and packaging

Appearance

A metered-dose aerosol containing a white to off-white suspension with a dose control valve.

Package unit

120 doses/can

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.