Daehan Lidocaine Hydrochloride 1% Injection

Key information summary

Efficacy & effects

This medication is used for various anesthesia methods such as epidural anesthesia, conduction anesthesia, infiltrative anesthesia, and surface anesthesia. It is also effective in treating ventricular arrhythmia. Patients use this drug to ensure safe and comfortable anesthesia during surgery or procedures, and can also receive assistance when there are heart rhythm disturbances. This drug is used for anesthesia and the treatment of ventricular arrhythmia.

Dosage

[Anesthesia] Adults 1. Epidural anesthesia: 100-200 mg of lidocaine hydrochloride per administration (maximum recommended dose per administration is 200 mg). 2. Conduction anesthesia: 30-200 mg; for supporting nerve block, 30-100 mg; for minor nerve block, up to 50 mg (maximum recommended dose per administration is 200 mg). 3. Infiltrative anesthesia: 20-200 mg (maximum recommended dose per administration is 200 mg). 4. Surface anesthesia: Apply an appropriate amount or spray. [Medical Use] Adults 1.

Precautions

This drug is a local anesthetic used for epidural anesthesia, and should not be administered to certain patients. For example, patients with severe bleeding or in shock, those with inflammation at the injection site or suffering from sepsis, and those allergic to this drug or other amide-type local anesthetics should avoid its use. Additionally, care must be taken when administering to patients with central nervous system disorders, pregnant women, the elderly, patients with severe hypertension, and those with significant spinal deformities. When using this drug, careful monitoring of the patient's condition is necessary as shock or toxicity symptoms may occur, and administration should be stopped immediately if abnormal symptoms develop, followed by appropriate treatment. Rarely, a serious side effect known as malignant hyperthermia may occur, characterized by a rapid rise in temperature, muscle rigidity, changes in blood color, hyperventilation, and sweating. If these symptoms are observed, immediately discontinue drug administration and seek professional treatment, and hydration is also important to prevent kidney damage. Central nervous system effects may lead to tremors, convulsions, drowsiness, anxiety, dizziness, nausea, and other symptoms, requiring prompt action if they occur. Additionally, allergic reactions may result in skin rashes or swelling, so caution is necessary. When using this drug, it should be administered slowly in minimal amounts, and intravenous injection should always be confirmed. Special caution is required when used with vasoconstrictors as there is an increased risk of side effects in certain patient groups. The safety of this drug in pregnant women has not been sufficiently established, so it should only be administered when the benefits of treatment are deemed to outweigh the risks. Elderly patients may be more sensitive to this drug, making dosage adjustments and monitoring of patient status important. Careful administration is also necessary in patients with impaired liver and kidney function due to potential toxicity risks. This drug may interact with certain other medications, so patients taking other drugs must inform their healthcare provider. Caution is especially needed when used in combination with antiarrhythmics, antidepressants, and vasoconstrictors. Finally, the metabolites of this drug have shown potential for mutagenesis and tumor formation in animal studies, so it is advisable not to use it at high concentrations for prolonged periods. It should not be used for ophthalmic purposes, and it is prudent to be prepared for emergency treatment during local anesthesia.

Side effects

Urticaria, edema, facial pallor, respiratory depression, anaphylactic reaction, malignant hyperthermia, shock, convulsions, hypotension, cardiac arrest, symptoms of intoxication, paralysis, severe allergic reactions, severe malignant hyperthermia, severe edema or urinary abnormalities, serious neurological symptoms.

Alternatives / Same-ingredient medications

• Jeil Lidocaine Injection Solution

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• Huwons Lidocaine Hydrochloride Hydrate Injection 2%

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• Daehan Lidocaine Hydrochloride 2% Injection

  Same ingredient
• Alirco Hydrochloride Lidocaine Jelly 2%

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