Daehan Lidocaine Hydrochloride 2% Injection

Key information summary

Efficacy & effects

This medication is used for various anesthesia methods such as epidural anesthesia, regional anesthesia, infiltration anesthesia, and surface anesthesia. It also aids in the treatment of cardiac diseases such as ventricular arrhythmia. Therefore, it is used to effectively manage both anesthesia and cardiac arrhythmias.

Dosage

[Anesthesia] 1. Epidural anesthesia: 200mg per dose (based on lidocaine hydrochloride) 2. Regional anesthesia: 40-200mg per dose, 60-120mg for supportive nerve blocks 3. Infiltration anesthesia: 40-200mg per dose 4. Surface anesthesia: apply or spray an appropriate amount [Medical usage] 1. Intravenous single administration method: 50-100mg (1-2mg/kg) infused slowly intravenously over 1-2 minutes; if ineffective, administer the same dose again after 5 minutes.

Precautions

This medication should not be used in patients with toxic bleeding or in shock, patients with inflammation at the injection site, sepsis patients, and those with allergies to this drug or similar local anesthetics. Caution is required in women who are pregnant, the elderly, patients with severe central nervous system diseases, patients with severe hypertension, and those with severe spinal deformities. When using this medication, watch for shock symptoms such as sudden drops in blood pressure or facial pallor, and if any abnormal symptoms appear, stop using the drug immediately and seek appropriate treatment. Severe hyperthermia, muscle rigidity, arrhythmias, and respiratory distress may rarely occur, so if these symptoms appear, immediate discontinuation and professional treatment are necessary. Due to effects on the central nervous system, symptoms such as tremors, convulsions, drowsiness, anxiety, dizziness, and nausea may occur, and any symptoms should be reported immediately. Allergic reactions like skin rash or swelling may occur, so caution is advised. The risk of side effects may increase when used with vasoconstrictors, so in patients with specific conditions or those with hypertension, heart disease, diabetes, etc., it is recommended to avoid adding vasoconstrictors or to use them cautiously. Pregnant women should only use this medication when the benefits of treatment outweigh the risks, as its safety has not been fully confirmed. In the elderly, the medication's effects may occur more strongly or side effects may occur more easily, so dose adjustments and close monitoring of the condition are recommended. This medication should be used cautiously in patients with impaired liver and kidney function, and due to possible drug interactions leading to increased blood concentration, consultation with healthcare professionals regarding concomitant medications is essential. Long-term use at high concentrations may pose a risk of mutagenesis, so it is advisable to avoid prolonged high-dose use when possible. When used as a local anesthetic, it is not suitable for surface anesthesia in the airway, and it should not be used for ophthalmic purposes. This medication should not be used in patients with severe cardiac conduction disorders or hypersensitivity, as it may affect cardiac function, warranting frequent monitoring of electrocardiograms and blood pressure during administration. In case of adverse reactions, inform healthcare professionals immediately for appropriate treatment.

Side effects

Facial pallor, shock, hives, severe swelling, anaphylactic reactions, high fever, severe skin reactions (severe rash, blisters, skin peeling, mucosal pain), difficulty breathing, respiratory depression, malignant hyperthermia, liver abnormalities (jaundice not specified but may accompany renal failure), central nervous system symptoms (tremors, seizures, loss of consciousness, paralysis), cardiac arrest, hypotension, bradycardia

Alternatives / Same-ingredient medications

• Jeil Lidocaine Injection Solution

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• Huwons Lidocaine Hydrochloride Hydrate Injection 2%

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• Daehan Lidocaine Hydrochloride 1% Injection

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• Alirco Hydrochloride Lidocaine Jelly 2%

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