Medication info

Innofurix Tablet (Inosiphlex)

Prescription medicationApproval withdrawn
Ingredient · strength
Inosiplex›Strength being verified
Manufacturer / importer
Vivozon Pharmaceutical Co., Ltd.
Appearance
This medication is a white or off-white tablet.
Packaging
8, 60, 120, 500 tablets
Approval status
Approval withdrawn

MFDS item code 198000234 · Notified 1980.03.27

This product's status changed to Approval withdrawn on 2023.03.14. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of viral infections (herpes simplex, herpes zoster, chickenpox, etc.)
Who uses it
Adults · Children
Adult dosage
(Tablets) Adults: Administer 3~4 g of inosiplex daily orally in divided doses of 500 mg~1 g every 4~6 hours. (Syrup) Adults: Administer 3~4 g daily (60~80 mL of this medicine) orally in divided doses of 500 mg~1g (10~20 mL) every 4~6 hours.
Children's dosage
(Tablets) Children: Administer 50~100 mg per kg of body weight daily of this medicine orally in 6 divided doses. (Syrup) Children: Administer 50~100 mg per kg of body weight daily orally in 6 divided doses.

Ingredients

Manufacturer
Vivozon Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of viral infections (herpes simplex, herpes zoster, chickenpox, etc.)

  • Herpes simplex
  • herpes zoster
  • varicella
  • measles
  • subacute sclerosing panencephalitis
View approved original text

This medication is used to treat various viral infections, such as herpes simplex, herpes zoster, and varicella. It is also effectively used for conditions like measles occurring in immunocompromised patients and for a rare but severe neurological condition called subacute sclerosing panencephalitis (SSPE).

Dosage and Administration

Adult dosage

(Tablets) Adults: Administer 3~4 g of inosiplex daily orally in divided doses of 500 mg~1 g every 4~6 hours. (Syrup) Adults: Administer 3~4 g daily (60~80 mL of this medicine) orally in divided doses of 500 mg~1g (10~20 mL) every 4~6 hours.

Children's dosage

(Tablets) Children: Administer 50~100 mg per kg of body weight daily of this medicine orally in 6 divided doses. (Syrup) Children: Administer 50~100 mg per kg of body weight daily orally in 6 divided doses.

Precautions

This medication should not be administered to patients who have had an allergic reaction to it or any of its components. Patients with gout or hyperuricemia, or a history of such conditions, should use this medication with caution, as it may exacerbate symptoms by increasing blood uric acid levels. Patients with urinary stones or kidney stones should also use this medication carefully, as it may increase uric acid levels in the blood or urine, worsening stone symptoms. Patients with impaired kidney function should be cautious with this medication, as it may delay uric acid excretion and lead to side effects. Patients taking cardiac medication digoxin should administer this medication carefully, as it may exhibit slight cardiac activity. Taking this medication may cause gastrointestinal symptoms such as dyspepsia, diarrhea, constipation, nausea, vomiting, and abdominal pain. There may also be hematological abnormalities such as increased red blood cell count, decreased white blood cells, and increased platelets. Liver function tests may show elevated levels, so attention to liver health is advised. Allergic reactions such as skin rashes may occur infrequently. This medication may elevate blood uric acid levels and potentially induce hyperuricemia. Effects on the kidneys and urinary tract may lead to elevated blood urea nitrogen (BUN), kidney stones due to hypercalcemia, increased urine volume, and urinary stones. Neurological symptoms like headaches, dizziness, fatigue, malaise, irritability, drowsiness, and insomnia may also occur. Joint pain or, rarely, interstitial pneumonia may also present; any symptoms should be reported immediately. As this medication may increase uric acid levels in the blood and urine, regular monitoring of uric acid levels and kidney function during treatment is recommended. While there are no specific severe drug interactions with this medication, it is advisable to avoid taking it with cortisone, globulin, immunosuppressants, or anti-lymphocyte globulin. The safety of this medication during pregnancy has not been established, so it is recommended to avoid use during the first three months of pregnancy; if administration during pregnancy is necessary, it should only be after consulting a physician when the benefits outweigh the risks. Animal studies have shown that this medication is excreted in breast milk, so it is preferable to discontinue use while nursing. In cases of overdose, symptoms such as vomiting, headaches, upper abdominal discomfort, dizziness, and palpitations may occur; however, reducing the dosage or discontinuing use will resolve the symptoms. In cases of overdose, symptomatic and supportive treatment should be implemented.

Side effects

abdominal discomfort, diarrhea, constipation, gastrointestinal bleeding, nausea, vomiting, stomach pain, increased red blood cells, decreased white blood cells, increased platelets, elevation of AST/ALT, elevation of γ-GTP, elevation of ALP, elevation of LDH, rash, hyperuricemia, elevated BUN, kidney stones associated with hypercalcemia, polyuria, urinary stones, headache, dizziness, fatigue, malaise, irritability, drowsiness, insomnia, arthralgia, interstitial pneumonia, palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that blocks light and prevents air from entering. It should also be stored at room temperature, avoiding excessively hot or cold locations.

Appearance and packaging

Appearance

This medication is a white or off-white tablet.

Package unit

8, 60, 120, 500 tablets

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.