Hymetin Tablet (Cimetidine)

Adult dosage

For adults, 400 mg orally twice daily (morning, bedtime) or 800 mg once daily at bedtime. 300 mg can be administered orally four times a day (after meals, at bedtime), and the dosage can be increased to 400 mg four times a day (total 1.6 g). During acute exacerbations of acute or chronic gastritis, 200 mg can be administered twice a day or 400 mg once daily. Antacids may be given as needed.

Children's dosage

Administered orally in divided doses of 20-40 mg per kg of body weight per day.

This medication should be handled very carefully when the injection form is involved, as glass fragments may enter when cutting glass ampoules, especially when administering to children and elderly patients. It should not be administered to patients with known allergies to this drug or its ingredients, those with a history of hypersensitive reactions, patients at high risk of ventricular arrhythmias, and those with certain genetic lactose-related diseases. Patients with impaired kidney or liver function, those with drug allergies, elderly patients, children under 19 years old, and patients on dialysis need to adjust their dosages or take special precautions when using this medication. This drug can cause various side effects such as reduction in blood cell counts, liver dysfunction, kidney impairment, allergic reactions, endocrine disorders, gastrointestinal symptoms, neurological disturbances, and skin reactions, so if abnormal symptoms occur, immediate consultation with medical personnel is required. During treatment, it is advisable to closely monitor disease progression and consider changing treatment methods if there is no effect or if side effects are severe. This medication has many interactions with other drugs, and caution should be taken as blood concentration may change when taken alongside anticoagulants, antidepressants, antiarrhythmics, antibiotics, and more. Since safety has not been established during pregnancy, it should be used with caution, and breastfeeding should be discontinued as it passes into breast milk. Safety has not been fully confirmed for children, so it should only be administered when absolutely necessary, and the dosage may need to be adjusted for elderly patients due to decreased kidney function. In case of overdose, serious symptoms such as respiratory depression may occur, requiring immediate emergency treatment. When administered as an injection, slow infusion should be performed to prevent arrhythmias or hypotension that may occur due to rapid injection. Store out of reach of children, as transferring to another container can cause quality deterioration or accidents.

Serious side effects

• Leukopenia
• agranulocytosis
• thrombocytopenia
• pancytopenia
• aplastic anemia
• immune hemolytic anemia
• jaundice
• hepatitis
• elevated AST
• ALT

Mild side effects

• Dizziness
• headache
• drowsiness
• abdominal distension
• constipation
• diarrhea
• fatigue
• fever
• general feeling of warmth
• difficulty urinating

This medication should be stored in a tightly sealed container that is airtight and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the drug for a longer period.

Appearance

White round film-coated tablets

Package unit

500 tablets/bottle