Key information summary
Efficacy & effects
This medication is primarily used for various edema symptoms such as hypertension (essential and renal hypertension), cardiac edema due to heart failure, renal edema, hepatic edema (ascites), and peripheral vascular edema. The injectable form is also utilized in the treatment of acute pulmonary edema. This drug helps to lower blood pressure and reduce the excess fluid accumulated in the body, thereby alleviating symptoms. It is used appropriately for managing various types of edema and hypertension according to the route of administration for tablets and injections. Overall, it effectively treats edema and blood pressure issues related to cardiovascular and renal diseases.
Dosage
Oral: As furosemide, administer 20-80 mg once daily or every other day by mouth. If sufficient effect is not observed, increase by 20-40 mg every 6-8 hours and administer 1-2 times daily. In severe cases, it can be administered up to 600 mg per day. For hypertension, administer 80 mg daily in two divided doses. If sufficient effect is not observed, combine with other antihypertensive drugs. Injectable: Once daily.
Precautions
This medication is a potent diuretic that expels excess water and sodium from the body. Severe dehydration and electrolyte imbalances may occur in case of overdose; therefore, regular blood tests are necessary. Patients with allergies to this medication or certain kidney and liver diseases, as well as pregnant and breastfeeding women, should not take this medication. Patients who have difficulty urinating may experience discomfort when taking this drug, so caution is required. Patients with low blood pressure, diabetes, gout, liver cirrhosis, etc., need careful monitoring while taking this medication. Elderly patients are at a higher risk of dehydration and dizziness or fainting due to low blood pressure while taking this drug, so they should be cautious. During treatment, blood sodium, potassium, and creatinine levels should be checked regularly, and extra caution should be exercised if symptoms like vomiting or diarrhea occur. This medication may interact with certain drugs, increasing the risk of side effects when used together, so consultation with a healthcare provider is necessary. During pregnancy, this medication should generally be avoided unless absolutely necessary, as it may affect the fetus, and it should be avoided while breastfeeding. In case of overdose, immediate medical attention should be sought to receive appropriate treatment and electrolyte correction. This medication should be stored out of reach of children and should not be transferred to other containers.
Side effects
Urticaria, severe swelling (edema), anaphylactic reaction, anaphylactoid reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis, similar to pemphigus, acute generalized pustular dermatitis, respiratory distress, liver abnormalities (jaundice), hepatic encephalopathy, severe hypotension, severe neurological symptoms (delirium, flaccid paralysis, confusion, loss of consciousness), severe edema, acute renal failure, thrombosis, shock
