Dapari Zinc 10mg (Dapagliflozin Monohydrate Mixture)

Adult dose

The recommended dose of this medication for monotherapy and add-on combination therapy with other hypoglycemic agents such as insulin is 10mg once daily. In the initial combination therapy with metformin, the initial recommended dose is 5mg or 10mg once daily. This medication can be taken orally once daily at any time regardless of food intake. The tablet must be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years of age have not been established. There are no relevant data.

This medication should not be used in patients with a known hypersensitivity to the active ingredient or any excipients. It should also not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Patients with genetic disorders such as lactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take this medication. It should not be used in patients undergoing dialysis. In patients with fluid volume depletion or impaired kidney function, this medication should be used with caution. This medication can lower blood pressure and affect kidney function, so blood pressure and kidney status must be closely monitored before and during treatment. Especially in elderly patients or those taking diuretics, there is a higher risk of hypotension or reduced blood volume, requiring careful attention. This medication contains dyes Yellow No. 4 and Yellow No. 5, so individuals allergic or hypersensitive to these components should take it with caution. Taking this medication may lead to genital or urinary tract infections, so if symptoms of infection appear, immediate consultation with a healthcare provider is essential. Additionally, hypoglycemic symptoms may occur, thus it may be necessary to adjust the dosage when used in conjunction with other diabetes medications such as insulin or sulfonylureas to reduce the risk of hypoglycemia. Symptoms of dehydration or hypotension due to fluid volume reduction may occur, so if dizziness or dry mouth is experienced, inform your healthcare provider. Rarely, serious complications such as diabetic ketoacidosis may occur, so if symptoms like vomiting, abdominal pain, or difficulty breathing appear, immediate treatment is required. Pregnant or breastfeeding women are advised not to use this medication, and if pregnancy is confirmed, discontinuation of use should occur. In the case of overdose, there is no specific antidote, and treatment should be symptomatic, with appropriate measures taken for any symptoms of dehydration or hypotension. This medication does not significantly affect driving or the operation of machinery, but caution is necessary due to the risk of hypoglycemia. The safety and efficacy of this medication have not been established in children.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, breathlessness with cough and fever, yellowing of the skin or eyes, profound fatigue, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Vulvitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• fluid volume depletion
• dizziness
• constipation
• dry mouth
• back pain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. This will help preserve the drug's effectiveness and prevent deterioration.

Appearance

Yellow, biconvex, diamond-shaped film-coated tablets

Package unit

28 tablets/box [14 tablets/ptp X2], 30 tablets/bottle