Pregabalin Capsule 25 mg (Pregabalin)

Adult dosage

This medication is administered orally without regard to meals, divided into two doses daily. 1. Neuropathic pain - Peripheral neuropathic pain: The starting dose is 150 mg per day, which may be increased to 300 mg per day after 3 to 7 days. Further increases up to a maximum of 600 mg per day may be made at 7-day intervals. - Central neuropathic pain: Starting dose is 150 mg per day.

Children's dosage

Due to insufficient safety and efficacy data, use in children under 12 years old and adolescents aged 12 to 17 is not recommended.

This medication may increase the risk of suicidal thoughts or behavior, thus mood or behavior changes should be closely monitored during use. Patients with hypersensitivity to this medication or with genetically determined lactose intolerance should not take it. Diabetic patients should be aware that weight gain may affect blood sugar control. Immediate discontinuation of the medication is necessary if serious allergic reactions such as angioedema occur. Elderly patients should be cautious due to risks of dizziness or drowsiness, which may lead to injuries, and may experience vision changes such as blurred vision. Discontinuing this medication suddenly can result in withdrawal symptoms such as insomnia, headaches, or anxiety, and should be tapered off gradually under medical guidance. Due to the potential for drug abuse or dependence, patients must inform healthcare providers of their mental health status and history of drug use. Patients with impaired renal function may require dosage adjustments. Patients with heart disease should take this medication with caution. Due to its central nervous system depressant effects, there may be increased risk of respiratory depression when used with opioids or other depressants. During early pregnancy, there is a risk of fetal malformations; therefore, women who are pregnant or planning to become pregnant must consult their healthcare provider and use effective contraception. Breastfeeding women should discuss with their doctor whether to discontinue breastfeeding or the medication since it may be passed into breast milk. Risky activities such as driving or operating machinery should be avoided until the dizziness or drowsiness from the medication has resolved. In the event of severe skin reactions, the medication should be immediately discontinued, and healthcare providers should be notified. In case of overdose, immediate hospital care is required, and blood dialysis may be performed if needed. This medication should be stored out of reach of children, and should not be transferred to other containers for safety.

Serious side effects

Urticaria, severe swelling (angioedema, facial swelling, swelling around the mouth and upper airway), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, Stevens-Johnson syndrome, toxic epidermal necrolysis, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy.

Mild side effects

• Dizziness
• drowsiness
• confusion
• spatial disorientation
• increased sensitivity
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication should be stored in a sealed container to prevent air and moisture ingress, preferably in a cool place between 15 and 30 degrees Celsius. Storing it this way will help maintain its effectiveness over time.

Appearance

A hard capsule with a pale yellow upper part and white lower part containing a white powder that is white or light yellow.

Package unit

30 capsules per bottle