Antikranjeong 625 mg (Amoxicillin and Clavulanate Potassium)

Adult dose

Adults and children over 12 years old or weighing more than 40 kg should take 250 mg/125 mg of amoxicillin/clavulanate potassium orally three times a day every 8 hours. In cases of severe and respiratory infections, the dosage may be increased to 500 mg/125 mg. For patients with renal impairment, dosage should be adjusted based on creatinine clearance. - Creatinine clearance greater than 30 mL/min: dosage adjustment is not necessary.

Child dose

Children over 12 years old or weighing more than 40 kg should receive the same dosage as adults. In pediatric cases with renal impairment, the dosage should be reduced accordingly.

This medication is a beta-lactam antibiotic and should not be used in patients who are allergic or have had hypersensitivity reactions to penicillin. Patients with infectious mononucleosis or lymphocytic leukemia are at higher risk of rash and should be monitored closely. Patients with impaired liver function or a history of liver disorders should also use this medication with caution, and dosing intervals should be adjusted in cases of moderate to severe kidney impairment. Patients with allergic dispositions, elderly individuals, or those with poor nutritional status may experience side effects such as vitamin K deficiency, so caution is advised. If any unusual symptoms such as diarrhea, abdominal pain, skin rash, or difficulty breathing occur during the course of treatment, usage should be stopped immediately and medical advice sought. Regular liver and kidney function tests should be conducted, and prolonged use should be monitored for the development of resistant bacteria and superinfection with non-susceptible organisms. Pregnant women in early pregnancy or those who are breastfeeding should use this medication cautiously and it is advisable to avoid its use if possible. This medication may interact with other drugs, therefore, it is essential to inform healthcare providers of any other medications being taken. In case of overdose, symptoms such as vomiting, diarrhea, kidney failure, and convulsions may occur, requiring immediate medical attention. Store in a dry place at or below 25 degrees Celsius and adhere strictly to the prescribed dosage and administration as directed by a physician.

Serious side effects

• Hives
• swelling
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• severe allergic reactions
• fever accompanied by severe rash
• blisters
• skin peeling

Mild side effects

• Diarrhea
• membranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This medication is contained in a tightly sealed container to prevent moisture and should be stored in a cool temperature between 1 and 25 degrees Celsius. It is important to avoid direct sunlight or high temperatures and not to place it in humid areas.

Appearance

The tablets are white or nearly white, oval-shaped, and film-coated.

Package unit

40 tablets (4 tablets/PTP x 10)