Crestive Tablet 10/10 mg

Adult dose

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, treatment starts at 10/5 mg once daily, and the dose can be adjusted within the range of 10/5 mg to 10/20 mg as needed. After dose adjustment, lipid levels should be checked at intervals no less than 4 weeks, and dosage may be increased up to a maximum of 10/20 mg daily.

This medication can rarely cause rhabdomyolysis, leading to severe kidney dysfunction, so if acute muscle pain or muscle weakness occurs, consult a doctor immediately. It should not be used in patients with severely impaired liver function or active liver disease, and treatment should be discontinued or adjusted if liver enzyme levels are abnormally high. Patients with muscle diseases or a history of muscle-related issues should consult a doctor before taking this medication, as the risk of muscle injury may increase depending on concomitant medications. Pregnant women or those who may become pregnant, as well as nursing mothers, should not use this medication. If planning to become pregnant, appropriate contraceptive methods should be employed. Elderly patients or those with impaired kidney function may be at higher risk for muscle damage while taking this medication, so regular check-ups and monitoring are necessary. This medication may interact with certain drugs, so inform your doctor or pharmacist if you are currently taking any medications, especially when used in conjunction with fibrates, cyclosporine, anticoagulants, etc. If symptoms such as muscle pain, fatigue, or fever occur during use, immediately inform healthcare personnel, and if necessary, blood tests should be conducted to check for muscle damage. Additionally, this medication contains lactose and should not be taken by patients with lactose intolerance. Caution is advised when driving or operating machinery as dizziness may occur. Safety and efficacy in children and adolescents have not been sufficiently confirmed, therefore it is not recommended for this age group. When storing this medication, keep it out of reach of children and do not transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Nasopharyngitis
• joint pain
• headache
• increased ALT
• increased AST
• muscle pain
• elevated blood bilirubin
• acneiform dermatitis
• pruritus
• dizziness

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the medication's effectiveness for an extended period.

Appearance

White to nearly white round film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]