Vistar Tablets 10/20mg

Adult dose

This medication should be administered once daily in the evening regardless of meals. Patients with primary hypercholesterolemia may be given a dose within the range of 10/10mg to 10/40mg daily, with the generally recommended initial dose being 10/20mg daily. Patients with less need for LDL-cholesterol reduction may start at 10/10mg daily. The recommended dose for patients with homozygous familial hypercholesterolemia is 10/40mg daily.

This medication may cause serious muscle-related side effects, such as myopathy and rhabdomyolysis, so if muscle pain or weakness occurs, you must consult a doctor immediately. This medication should not be used by individuals who are allergic to its components, those with severely impaired liver function, and those who are pregnant or breastfeeding. Particularly, this medication may harm the fetus during pregnancy, so women planning to become pregnant or who may be pregnant should consult a doctor before taking it, and should immediately discontinue use if pregnancy is confirmed. The risk of muscle damage significantly increases when this medication is used with potent CYP3A4 inhibitors, including certain antifungals, antibiotics, and antivirals, so these should not be taken together. Additionally, this medication should not be used in combination with certain other medications, such as gemfibrozil, cyclosporine, or danazol; consult a doctor for appropriate alternative medications if necessary. This medication contains lactose, so it should not be taken by patients with lactose intolerance or related genetic disorders. Elderly patients, those with impaired kidney function, and those with hypothyroidism should be monitored closely due to increased risk of myopathy. To reduce the risk of myopathy, regular blood tests to check muscle enzyme levels are recommended during the course of this medication. The risk of myopathy may increase if other interacting medications are taken, so always consult a doctor or pharmacist when starting or stopping any new medication. If unexplained muscle pain, tenderness, or weakness occurs during treatment, notify healthcare professionals immediately and stop taking this medication. Patients with impaired liver function or a history of liver disease should have regular liver function tests before and after taking this medication, and should stop taking it if symptoms of liver damage occur. This medication can rarely cause respiratory issues such as interstitial lung disease, so consult a healthcare professional if experiencing shortness of breath or persistent cough. Blood sugar levels may rise during the use of this medication, so patients at high risk for diabetes should check their blood sugar regularly. In clinical trials and post-marketing surveillance, this medication has generally demonstrated excellent tolerability, but side effects such as headaches, indigestion, diarrhea, cold symptoms, and muscle pain have been reported. There is limited data on safety in children and adolescents, therefore its use in children under 10 years of age is not recommended. Patients taking this medication should inform other physicians when prescribed new medications and should not discontinue or alter dosages arbitrarily.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, yellowing of the skin or eyes (jaundice), general malaise, sudden and severe headache, thunderclap headache, seizures, confusion, vision changes, paralysis, significantly reduced urine output, severe generalized edema with elevated blood pressure, anaphylaxis

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• abdominal pain
• viral infection
• pharyngitis

This medication should be stored in a tightly sealed container to protect it from exposure to air and moisture, and should be kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy and prevents degradation.

Appearance

White to off-white, bilaterally convex rectangular tablet

Package unit

30 tablets (10 tablets/PTP x 3)