Anafo Injection (Nepafenac Hydrochloride)

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is advisable to have the patient lie still and rest for 15-20 minutes. When added to an infusion solution such as an electrolyte or glucose solution, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the administration time. It is recommended to avoid mixing this drug with other drugs for injection. Adjust the dose as appropriate according to age and symptoms.

This medication is in injection form, and when opening the container, glass fragments may enter; therefore, it should be opened safely and cautiously. Patients with epilepsy or myocardial infarction, those taking certain medications, and those allergic to this drug or its components should not use it. Children under 15 years of age and individuals with a history of seizures or difficulty urinating due to urethral and prostate issues, as well as patients with glaucoma who have high eye pressure, are advised against using this drug. Elderly patients, pregnant or breastfeeding women, and those taking anticholinergic medications should use this drug with caution. This drug may cause various side effects, including loss of appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, rapid heartbeat, dry mouth, and difficulty urinating. Additionally, it may rarely cause headaches, blurred vision, fatigue, nervousness, sleep disturbances, hallucinations, seizures, and allergic reactions, so caution is necessary. While this drug helps alleviate inflammation and pain, it is not a treatment for the underlying cause, thus its use should be considered based on the severity of symptoms. When used for infectious inflammation, appropriate antibiotics or antifungals should be administered alongside, and the patient's condition should be closely monitored. In the elderly, it should be administered with the minimum dose and with caution, and those with liver or kidney dysfunction should be careful as it may affect drug metabolism and excretion. This drug may cause drowsiness or decreased behavior, so it is advised not to use it when engaging in activities requiring attention, such as driving or operating machinery. When used in combination with other analgesics or certain medications, side effects may increase, so consultation with a professional is necessary when administered together. Use of this drug is not recommended in pregnant or breastfeeding women. It should not be used in children as its safety and efficacy have not been established, and it is not recommended for the elderly due to anticholinergic side effects. In case of overdose, consult a doctor or pharmacist immediately, and monitoring of cardiac and respiratory function may be necessary. It is recommended to avoid mixing this drug with other medications for injection. When storing, keep it out of reach of children and avoid direct sunlight while storing in a cool, dry place that is not exposed to moisture. Furthermore, it is important not to transfer it to other containers to prevent misuse.

• Loss of appetite
• gastrointestinal disorders
• nausea
• drowsiness
• vomiting
• hyperhidrosis
• dizziness
• tachycardia
• palpitations
• thirst

This drug should be stored in a sealed container to avoid exposure to air, and the storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. This way, the effectiveness of the drug can be safely preserved.

Appearance

A clear, colorless, odorless solution contained in a clear colorless ampoule injection

Package unit

20 ampoules/box [(2 milliliters/1 ampoule)], 50 ampoules/box [(2 milliliters/1 ampoule)]