Astroten 10 mg (Rosuvastatin Calcium)

Adult dose

This medication can be taken at any time of the day, with or without food. The initial dosage is 5 mg once daily, which can be adjusted to a maintenance dose of up to 10 mg once daily if needed. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and the patient’s response, with a maximum daily dose of 20 mg possible after 4 weeks or longer intervals.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), the usual dosage range is once daily 5 mg to 20 mg. The dosage should be adjusted according to individual treatment goals.

This medication should not be used in certain patients. For example, it is contraindicated in patients who are allergic to any of the components of this medication, have severe hepatic impairment, or have muscle disorders. It should also be avoided in patients with significantly impaired renal function, pregnant or breastfeeding women, and women of childbearing age who do not use appropriate contraceptive methods. Because this medication can affect liver function and muscles, it is important for patients with a history of hepatic disease or high alcohol consumption to have multiple liver function tests before administration. If symptoms of muscle pain or weakness occur, it is crucial to consult a doctor immediately, and in severe cases, the medication should be discontinued. This medication contains lactose, so it is not suitable for patients with lactose intolerance or specific genetic diseases. Furthermore, due to numerous interactions with other medications, patients should inform their doctor or pharmacist of any other medications they are currently taking. Particularly, the risk of muscle-related side effects may increase when taken with certain antiviral agents, immunosuppressants, antifungals, and antibiotics. Pregnant or breastfeeding women should not use this medication, and women who may become pregnant should use appropriate contraceptive methods during treatment. In case of overdose, there is no specific antidote, so treatment should be based on symptoms, and liver function as well as muscle enzyme levels should be monitored regularly. Serious side effects, such as interstitial lung disease, severe liver damage, myopathy, kidney problems, etc. can occur rarely, so if any abnormal symptoms appear, immediate consultation with healthcare professionals is necessary. Caution is needed when driving or operating machinery as dizziness may occur. Finally, this medication may exhibit higher concentrations in Asian populations, potentially necessitating dosage adjustments.

Serious side effects

• Allergic reactions including urticaria
• angioedema
• pancreatitis
• myopathy
• rhabdomyolysis
• severe muscle weakness
• ocular muscle weakness
• thrombocytopenia
• jaundice
• hepatitis

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to preserve the drug's efficacy and safety over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle