Medication info
Raberin Tablets 10 mg (Rabeprazole Sodium)

Raberin Tablets 10 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›10mg / 1 tablet
Manufacturer / importer
일양바이오팜(주)
Appearance
Pale yellow, round enteric-coated tablet
Packaging
28 tablets (14 tablets/AluAlu packaging x 2)
Approval status
Active

MFDS item code 200611303 · Notified 2006.11.20 · Insurance code 696600950

Summary

Main use
Relief of symptoms of gastric ulcer, duodenal ulcer, and gastroesophageal reflux disease, and treatment effect against Helicobacter pylori infection
Who takes it
Adults · Children
Adult dose
Administer Rabeprazole Sodium 10 mg orally once daily for adults. Depending on the symptoms, it may be given as 20 mg once daily. Administer for up to 8 weeks for gastric ulcer and up to 6 weeks for duodenal ulcer. For erosive or ulcerative gastroesophageal reflux disease, administer 10 mg or 20 mg orally once daily for 4 to 8 weeks. If untreated, an additional 8-week course of 10 mg or 20 mg may be given once daily.
Child dose
Safety for pediatric use has not been established.

Ingredients

Manufacturer
일양바이오팜(주)

Efficacy & effects

Relief of symptoms of gastric ulcer, duodenal ulcer, and gastroesophageal reflux disease, and treatment effect against Helicobacter pylori infection

  • Gastric ulcers
  • duodenal ulcers
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat ulcers that occur in the stomach and duodenum, alleviate symptoms of gastroesophageal reflux disease, and is also beneficial for long-term maintenance therapy. It is used in conjunction with antibiotics in patients with gastrointestinal ulcers infected with Helicobacter pylori to enhance therapeutic effects. It is also used in the treatment of Zollinger-Ellison syndrome. Thus, it is utilized for the treatment and symptom improvement of various gastrointestinal-related disorders.

How to take

Adult dose

Administer Rabeprazole Sodium 10 mg orally once daily for adults. Depending on the symptoms, it may be given as 20 mg once daily. Administer for up to 8 weeks for gastric ulcer and up to 6 weeks for duodenal ulcer. For erosive or ulcerative gastroesophageal reflux disease, administer 10 mg or 20 mg orally once daily for 4 to 8 weeks. If untreated, an additional 8-week course of 10 mg or 20 mg may be given once daily.

Child dose

Safety for pediatric use has not been established.

Precautions

This medication should not be used in patients with allergies to certain components. Caution is especially needed in cases of hypersensitivity to benzimidazoles, penicillins, or macrolide antibiotics. It is also safest for pregnant or nursing women to refrain from taking this medication. Use should be exercised with caution for patients with impaired liver function or the elderly. This drug may cause allergic reactions such as skin rashes and itching; if symptoms occur, immediate discontinuation of use is necessary. Regular blood tests are required as changes in red or white blood cell counts may occur. Liver function tests should also be carried out, and if abnormalities are found, the medication should be discontinued. Caution is advised for patients with cardiovascular diseases as it may affect the heart or blood pressure. Gastrointestinal symptoms such as diarrhea, abdominal pain, or nausea may occur, so consultation with a doctor is necessary if symptoms arise. Neurological symptoms such as headaches, dizziness, and insomnia may appear, indicating caution while driving or operating machinery. Respiratory symptoms or skin rashes have also been reported, so immediate disclosure to healthcare providers is crucial if abnormal symptoms occur. This medication may interact with other medications; therefore, it is essential to notify healthcare providers of any other medications being taken. Care is particularly needed when used in conjunction with antibiotics, antiviral agents, or anticoagulants. Long-term use may increase the risk of osteoporosis-related fractures, necessitating regular check-ups. Hypomagnesemia may occur, and magnesium levels in the blood should be monitored during long-term use or in conjunction with specific medications. The medication should be swallowed whole without chewing or crushing, and stored out of reach of children. During the intake of this medication, the risk of gastrointestinal infection may slightly increase, so if diarrhea persists, consultation with healthcare providers is warranted. It is safe to avoid this medication during pregnancy or breastfeeding, and the elderly should use it cautiously considering liver function status. There is no specific antidote for overdose, so appropriate treatment based on symptoms is necessary. Prolonged use of this medication may lead to impaired absorption of vitamin B12, requiring periodic testing. If abnormal reactions occur to the skin or systemically during medication use, immediate discontinuation and a consultation with a specialist are necessary. While this medication does not significantly affect driving ability, caution is needed as drowsiness may occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, fulminant hepatitis, liver dysfunction, jaundice, severe allergic reactions, severe skin adverse reactions (toxic epidermal necrolysis, Stevens-Johnson syndrome), respiratory issues (difficulty breathing, asthma, apnea, respiratory depression, interstitial pneumonia), serious neurological symptoms (headaches, convulsions, confusion, disorientation, stupor, seizures, hallucinations, sensory disturbance

Mild side effects

  • Rash
  • itching
  • reduction in red blood cells
  • reduction in white blood cells
  • increase in white blood cells
  • increase in eosinophils
  • increase in neutrophils
  • reduction in lymphocytes
  • anemia
  • petechiae
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  • lymphadenopathy
  • hypopigmented anemia
  • pancytopenia
  • agranulocytosis
  • reduction in platelets
  • hemolytic anemia
  • elevation of ALT
  • elevation of AST
  • elevation of ALP
  • elevation of γ-GTP
  • elevation of LDH
  • elevation of total bilirubin
  • hypertension
  • myocardial infarction
  • abnormal ECG
  • migraine
  • syncope
  • angina
  • heart block
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. Storing it this way helps preserve the medication's effectiveness.

Appearance and packaging

Appearance

Pale yellow, round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.